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LIF Rabbit pAb (bs-1058R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-1058R
英文名稱 LIF Rabbit pAb
中文名稱 白血病抑制因子抗體
別    名 Leukemia inhibitory factor; DIA; CDF; Cholinergic Differentiation Factor; D factor; differentiation inhibitory activity; Differentiation stimulating factor; Emfilermin; HILDA; Human interleukin in DA cells; LIF_HUMAN; Melanoma derived LPL inhibitor; Melanoma-derived LPL inhibitor; MLPLI.  
Specific References  (7)     |     bs-1058R has been referenced in 7 publications.
[IF=6.291] Peng Zheng. et al. Alleviative effect of melatonin on the decrease of uterine receptivity caused by blood ammonia through ROS/NF-κB pathway in dairy cow. Ecotox Environ Safe. 2022 Feb;231:113166  WB ;  Bovine.  
[IF=3.69] Kiyoshi Terawaki. et al. The ameliorating effects of tokishakuyakusan in a rat model of implantation failure involves endometrial gland leukemia inhibitory factor and decidualization. J Ethnopharmacol. 2021 Jan;265:113288  IHC ;  Rat.  
[IF=3.309] Gulistan Sanem Saribas. et al. Ellagic acid increases implantation rates with its antifibrotic effect in the rat model of intrauterine adhesion. PATHOL RES PRACT. 2023 Jun;246:154499  IHC ;  Rat.  
[IF=2.2] Cui, Na, et al. "The Roles of Anandamide, Fatty Acid Amide Hydrolase, and Leukemia Inhibitory Factor on the Endometrium during the Implantation Window." Frontiers in Endocrinology 8 (2017): 268.  IHC-P ;  Human.  
[IF=1.785] An J et al. A clinical and basic study of optimal endometrial preparation protocols for patients with infertility undergoing frozen?thawed embryo transfer. Exp Ther Med . 2020 Sep;20(3):2191-2199.  WB ;  Human.  
[IF=1.785] Junxia An. et al. A clinical and basic study of optimal endometrial preparation protocols for patients with infertility undergoing frozen?thawed embryo transfer. Exp Ther Med. 2020 Sep;20(3):2191-2199  WB ;  Human.  
[IF=1.18] Liang, Youde, et al. "Expression of LIF and LIFR in periodontal tissue during orthodontic tooth movement." The Angle Orthodontist 81.4 (2011): 600-608.  IHC-P ;  Rat.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  生長因子和激素  細(xì)胞周期蛋白  細(xì)胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 20 kDa
檢測分子量
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LIF: 101-202/202 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The leukemia inhibitory factor- LIF is a kind of cell factor that has various living creature functions.It has the leukemia cell of inducement to divide, regulating the growth metabolism of the bone organization, maintaining the basic characteristic of the Embryonicstem celles and promoting the mankind build the blood stem cell to divide to propagate, promote the cholinergic neuron to divide, obstruct the fat cell to synthesize, stimulate the muscle cell growth, regulate the liver cell to expect to respond the egg white to synthesize etc. in the acute the biology activity etc. function.

Function:
LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

Subcellular Location:
Secreted.

Similarity:
Belongs to the LIF/OSM family.

SWISS:
P15018

Gene ID:
3976

Database links:

Entrez Gene: 3976 Human

Entrez Gene: 16878 Mouse

Omim: 159540 Human

SwissProt: P15018 Human

SwissProt: P09056 Mouse

Unigene: 2250 Human

Unigene: 4964 Mouse



生長因子和激素( Growth Factor and Hormones)
白血病抑制因子-LIF是一種具有多種生物功能的細(xì)胞因子。它具有誘導(dǎo)白血病細(xì)胞分化,調(diào)節(jié)骨組織的生長代謝,維持胚胎干細(xì)胞(Embryonicstem celles細(xì)胞)的基本特征、促進(jìn)人類造血干細(xì)胞的分化增殖、促進(jìn)膽堿能神經(jīng)元的分化、阻礙脂肪細(xì)胞合成、刺激成肌細(xì)胞生長、調(diào)節(jié)肝細(xì)胞中急性期反應(yīng)蛋白的合成等生物學(xué)活性等作用.
產(chǎn)品圖片
Sample: Large intestine(mouse) Lysate at 40 ug U87mg cell(human) Lysate at 30 ug Primary: Anti- LIF (bs-1058R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 20kD Observed band size: 30/50 kD
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