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intestinal FABP Rabbit pAb (bs-0898R)  
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50ul/1180.00元
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產品編號 bs-0898R
英文名稱 intestinal FABP Rabbit pAb
中文名稱 小腸型脂肪酸結合蛋白抗體
別    名 FABP 2; FABP2; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein intestinal; Fatty acid-binding protein; I-FABP; I FABP; IFABP; Intestinal fatty acid binding protein 2; MGC133132; FABPI_HUMAN; Fatty acid binding protein intestinal; Fatty acid-binding protein 2; Fatty acid-binding protein; Intestinal fatty acid binding protein 2; Intestinal-type fatty acid-binding protein; OTTHUMP00000163925.  
研究領域 免疫學  生長因子和激素  激酶和磷酸酶  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Chicken)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IFABP: 31-132/132 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity). [Subcellular Location] Cytoplasm (By similarity). [Similarity] Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Function:
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.

Similarity:
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

SWISS:
P12104

Gene ID:
2169

Database links:

Entrez Gene: 2169 Human

Entrez Gene: 14079 Mouse

Entrez Gene: 25598 Rat

Omim: 134640 Human

SwissProt: P12104 Human

SwissProt: P55050 Mouse

SwissProt: Q53YP5 Mouse

SwissProt: P02693 Rat

Unigene: 282265 Human

Unigene: 28398 Mouse

Unigene: 91358 Rat



小腸脂肪酸結合蛋白(IFABP)主要是在小腸分泌的一種蛋白質,參與了脂肪酸的吸收和代謝。IFABP有可能通過干擾脂肪酸代謝而影響胰島素敏感性。 IFABP主要用于2型糖尿病相關性的研究。
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