超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
五月精品夜夜春夜夜爽久久,黄色网络在线观看,亚洲精品无码一区二区色戒
首頁 > 產品中心 > 一抗 > 產品信息
Phospho-Cyclin B1 (Ser126) Rabbit pAb (bs-3733R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-3733R
英文名稱 Phospho-Cyclin B1 (Ser126) Rabbit pAb
中文名稱 磷酸化周期素B1抗體
別    名 Cyclin B1(phospho S126); Cyclin B1(phospho-Ser126); p-Cyclin B1(S126); p-Cyclin B1(Ser126); p-Cyclin B1(phospho S126); CCNB 1; CCNB; CCNB1; CCNB1_HUMAN; G2 mitotic specific cyclin B1; G2/mitotic-specific cyclin-B1.  
產品類型 磷酸化抗體 
研究領域 腫瘤  細胞生物  免疫學  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 48 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Cyclin B1 around the phosphorylation site of Ser126: TA(p-S)PS 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].

Function:
Essential for the control of the cell cycle at the G2/M (mitosis) transition.

Subunit:
Interacts with the CDC2 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex. Binds HEI10. Interacts with catalytically active RALBP1 and CDC2 during mitosis to form an endocytotic complex during interphase. Interacts with CCNF; interaction is required for nuclear localization.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, centrosome.

Post-translational modifications:
Ubiquitinated by the SCF(NIPA) complex during interphase, leading to its destruction. Not ubiquitinated during G2/M phases.
Phosphorylated by PLK1 at Ser-133 on centrosomes during prophase: phosphorylation by PLK1 does not cause nuclear import. Phosphorylation at Ser-147 was also reported to be mediated by PLK1 but Ser-133 seems to be the primary phosphorylation site.

Similarity:
Belongs to the cyclin family. Cyclin AB subfamily.

SWISS:
P14635

Gene ID:
891

Database links:

Entrez Gene: 891 Human

Entrez Gene: 268697 Mouse

Entrez Gene: 25203 Rat

Omim: 123836 Human

SwissProt: P14635 Human

SwissProt: P24860 Mouse

SwissProt: P30277 Rat

Unigene: 23960 Human

Unigene: 260114 Mouse

Unigene: 380027 Mouse

Unigene: 482545 Mouse

Unigene: 9232 Rat



主要出現在G2期。Cyclin B是細胞周期調節必不可少的條件。 細胞周期素B1是細胞周期調節因子,它的異常表達將導致細胞周期發生紊亂,致使腫瘤形成.
產品圖片
Paraformaldehyde-fixed, paraffin embedded (Human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Phospho-Cyclin B1 (Ser126)) Polyclonal Antibody, Unconjugated (bs-3733R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Human esophageal carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Phospho-Cyclin B1 (Ser126)) Polyclonal Antibody, Unconjugated (bs-3733R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (human skin cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Phospho-Cyclin B1 (Ser126)) Polyclonal Antibody, Unconjugated (bs-3733R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Hela cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (Phospho-Cyclin B1 (Ser126)) polyclonal Antibody, Unconjugated (bs-3733R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久精品二区三区 | 精品色网站 | 亚洲免费人成视频观看 | 欧美亚洲日本国产黑白配 | 欧美一级淫片a免费播放口 日韩免费一级 | 国产呦精品一区二区三区网站 | 精品无人区无码乱码大片国产 | 亚洲AV成人午夜福利在线观看 | avtom影院永久地址 | 亚洲精品视频在线播放 | 久久久免费精品re6 正在播放白领少妇第一次 青青操在线观看 | 亚洲精品久久久久久国产 | av在线最新网址不卡最新 | www.avtvtv.com新网址 | 久久一区二区三区精华液 | 黄色地址在线观看 | 伊人aa| 午夜视频亚洲 | 亚洲国产主播一区 | AV无码专区亚洲AV极速版 | 国产精品一区二区男人吃奶 | 国产日韩三区 | 中文在线播放 | a级片在线免费观看视频 | www.爱爱视频 | 国产短视频在线观看 | 日本在线a片一区视频 | 精品日韩在线一区 | 日韩一区二区不卡 | 成人无码视频 | 欧美日韩第一 | 欧美人妻一区二区三区 | 色88888久久久久久影院 | 91久久色 | 蜜桃国精产品二三三区视频 | 日本黄色大片免费 | 精品国产乱码久久久久久鸭王1 | 在线成人免费网站 | 婷婷色婷婷开心五月四房播播 | 欧美aaa一级片 | yy6969久久亚洲精品 |