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Galectin 7 Rabbit pAb (bs-5809R)  
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產(chǎn)品編號 bs-5809R
英文名稱 Galectin 7 Rabbit pAb
中文名稱 半乳糖凝集素7抗體
別    名 Galectin7; Gal-7; GAL7; Galectin-7; HKL-14; Human keratinocyte lectin 14; Lectin galactoside binding soluble 7; LEG7_HUMAN; LGALS7; LGALS7B; p53-induced gene 1 protein; Pi7; PIG1; TP53I1.  
研究領域 腫瘤  細胞生物  免疫學  神經(jīng)生物學  細胞凋亡  細胞粘附分子  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat)
產(chǎn)品應用 ICC/IF=1:50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 15 kDa
檢測分子量
細胞定位 細胞核 細胞漿 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Galectin 7.: 31-100/136 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008].

Function:
Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.

Subunit:
Monomer.

Subcellular Location:
Cytoplasm. Nucleus. Secreted (Potential). Note=May be secreted by a non-classical secretory pathway.

Tissue Specificity:
Mainly expressed in stratified squamous epithelium.

Similarity:
Contains 1 galectin domain.

SWISS:
P47929

Gene ID:
653499

Database links:

Entrez Gene: 3963 Human

Entrez Gene: 653499 Human

Entrez Gene: 16858 Mouse

Entrez Gene: 29518 Rat

Omim: 600615 Human

SwissProt: P47929 Human

SwissProt: O54974 Mouse

SwissProt: P97590 Rat

Unigene: 558355 Human

Unigene: 707031 Human

Unigene: 20973 Mouse

Unigene: 6336 Rat



產(chǎn)品圖片
HUVEC cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (Galectin 7) polyclonal Antibody, Unconjugated (bs-5809R) 1:50, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
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