超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
天堂伊人,纯肉无遮挡h肉动漫在线观看3d,欧美日韩123区
首頁 > 產品中心 > 一抗 > 產品信息
Perilipin A+B Rabbit pAb (bs-6765R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-6765R
英文名稱 Perilipin A+B Rabbit pAb
中文名稱 脂滴包被蛋白A+B抗體
別    名 Lipid droplet associated protein; PERIA; PERIB; Perilipin A; Perilipin; Perilipin B; PerilipinA; PerilipinB; PLIN.  
Specific References  (2)     |     bs-6765R has been referenced in 2 publications.
[IF=5.37] James, Sally, et al. "Multiparameter Analysis of Human Bone Marrow Stromal Cells Identifies Distinct Immunomodulatory and Differentiation-Competent Subtypes." Stem cell reports 4.6 (2015): 1004-1015.  Human.  
[IF=4.357] Li et al. Morusin suppresses breast cancer cell growth in vitro and in vivo through C/EBPβ and PPARγ mediated lipoapoptosis. (2015) J.Exp.Clin.Cancer.Res. 34:137  WB ;  Human.  
研究領域 腫瘤  心血管  細胞生物  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse (predicted: Sheep,Chicken,Dog)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,Flow-Cyt=0.2ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 54-56 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Perilipin A+B: Mixed peptides 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.

Function:
Perilipin A: Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness.
Perilipin B: May be involved in development and maintenance of adipose tissue.

Subunit:
Perilipin A: Interacts with ABHD5.

Subcellular Location:
Perilipin A: Lipid droplet. Note=Lipid droplet surface-associated.
Perilipin B: Membrane; Peripheral membrane protein.

Tissue Specificity:
Perilipin A: Adipocytes.
Perilipin B: Milk lipid globules.

Post-translational modifications:
Perilipin A: Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet.
Perilipin B: Acylated; primarily with C14, C16 and C18 fatty acids.

DISEASE:
Perilipin A: Defects in PLIN1 are the cause of familial partial lipodystrophy type 4 (FPLD4) [MIM:613877]. FPLD4 is a form of lipodystrophy characterized by loss of subcutaneous adipose tissue primarily affecting the lower limbs, insulin-resistant diabetes mellitus, hypertriglyceridemia, and hypertension.
Perilipin B:

Similarity:
Perilipin A: Belongs to the perilipin family.
Perilipin B: Belongs to the perilipin family.

SWISS:
O60240

Gene ID:
5346

Database links:

Entrez Gene: 5346 Human

Entrez Gene: 103968 Mouse

Entrez Gene: 25629 Rat

Omim: 170290 Human

SwissProt: O60240 Human

SwissProt: Q8CGN5 Mouse

SwissProt: P43884 Rat

Unigene: 103253 Human



產品圖片
Sample: HepG2 Cell (Human) Lysate at 30 ug Primary: Anti-Perilipin A+B (bs-6765R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54-56kD Observed band size: 50kD
Sample: Stomach (Mouse) Lysate at 40 ug Primary: Anti-Perilipin A+B? (bs-6765R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54-56 kD Observed band size: 56 kD
This image was generously provided by James Fox, PhD. at the University of York. Immunostaining of perilipin-positive adipocytes (red) using Rabbit Anti-Perilipin A+B Polyclonal Antibody (bs-6765R) in bone marrow of IL-7cre Rosa26-EYFP mice with DAPI (blue) nuclear counterstain.
Blank control: U937 (fixed with 2% paraformaldehyde (10 min)). Primary Antibody:Rabbit Anti- Perilipin A+B antibody(bs-6765R), Dilution: 0.2μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.
Blank control: MCF7(blue). Primary Antibody: Rabbit Anti-Perilipin A+B/AF647 Conjugated antibody (bs-6765R-AF647), Dilution: 5μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG/AF647(orange) ,used under the same conditions.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲无人区在线观看AV | 亚洲精品久久AV无码蜜桃第1集 | 在线观看国精产品一区 | 国内毛片免费看 | 黄色av免费观看 | 人妻无码中文字幕一区二区三区 | 欧美hhh | 插插射啊爱视频日a级 | 鲁大师在线影院免费观看 | 无码伊人久久大杳蕉中文无码 | 亚洲AV中文无码乱人伦在线R▽ | 久久导航精品一区 | 一本精品中文字幕在线 | 日韩精品一区二区在线天天狠天 | 亚洲男人天堂2017 | 69久久夜色精品国产7777 | 亚洲人和日本人hd | 无码伊人久久大杳蕉中文无码 | 国产精品嫩草影院一二三区入口 | 欧美做受高潮1 | 亚洲色成人一区二区三区小说 | 艳妇乳肉豪妇荡乳7 | 91麻豆免费在线观看 | 91豆花视频| a级黄色毛片三 | 播放一级黄色片 | 曰本a级毛片 | 美女视频免费是黄的网站高清 | 自慰无码一区二区三区 | 久久只精品99品免费久23小说 | 国产精品国语版在线观看 | 曰韩三级 | 亚洲国产线路综合 | 亚洲夜夜夜| 激情一二区 | 亚洲精品一区二区三区白峰美 | 精品国产三级 | 中出在线视频 | 在线免费观看高清 | 国产偷窥洗澡视频 | 国产精品国产自产拍高清 |