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CD20L/MS4A3 Rabbit pAb (bs-7900R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-7900R
英文名稱 CD20L/MS4A3 Rabbit pAb
中文名稱 CD20樣蛋白抗體
別    名 CD20 antigen homolog; CD20 antigen like; CD20 antigen like protein; CD20 antigen-like protein; CD20L; hematopoietic cell 4 transmembrane protein; Hematopoietic-specific transmembrane protein 4; HTm4; IgE receptor beta subunit; Membrane-spanning 4-domains subfamily A member 3; Ms4a3; MS4A3_HUMAN; OTTHUMP00000235850; OTTHUMP00000235851; OTTHUMP00000235853.  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  干細胞  細胞周期蛋白  激酶和磷酸酶  細胞類型標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 23 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MS4A3/CD20L: 51-150/214 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 MS4A3 is a member of the membrane-spanning 4A gene family and displays unique expression patterns among hematopoietic cells and nonlymphoid tissues. MS4A3 is likely to play a role in signal transduction and may function as a subunit associated with receptor complexes. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.

Function:
Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP).

Subunit:
Interacts with CDKN3. Interacts with CDKN3-CDK2 complexes through its binding to CDKN3; this interaction facilitates dissociation of cyclin A from CDKN3-CDK2 complexes.

Subcellular Location:
Endomembrane system; Multi-pass membrane protein (By similarity). Cytoplasm, perinuclear region (By similarity). Note=Located in the perinuclear area.

Tissue Specificity:
Expressed specifically in hematopoietic cells and tissues.

Similarity:
Belongs to the MS4A family.

SWISS:
Q96HJ5

Gene ID:
932

Database links:

Entrez Gene: 932 Human

Omim: 606498 Human

SwissProt: Q96HJ5 Human

Unigene: 99960 Human



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