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DPP9 Rabbit pAb (bs-8294R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-8294R
英文名稱 DPP9 Rabbit pAb
中文名稱 二肽基肽酶9抗體
別    名 Dipeptidyl peptidase IV related protein 2; Dipeptidyl peptidase 9; Dipeptidyl peptidase IV related protein 2; Dipeptidyl peptidase IV-related protein 2; Dipeptidyl peptidase IX; Dipeptidyl peptidase like protein 9; Dipeptidyl peptidase-like protein 9; Dipeptidylpeptidase 9; Dipeptidylpeptidase IX; DKFZp762F117; DP 9; DP9; DPLP 9; DPLP9; DPP 9; DPP IX; DPP9; DPP9_HUMAN; DPRP 2; DPRP-2; DPRP2; FLJ16073.  
Specific References  (1)     |     bs-8294R has been referenced in 1 publications.
[IF=3.391] Hui Yang. et al. A combined proteomic and metabolomic analyses of the priming phase during rat liver regeneration. Arch Biochem Biophys. 2020 Oct;693:108567  WB ;  Rat.  
研究領域 腫瘤  細胞生物  免疫學  發育生物學  信號轉導  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Cow,Chicken,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 98 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DPP9/DPRP2: 501-600/863 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2.Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPRP2 (dipeptidyl-peptidase IV-related protein 2), also known as DPP9 (dipeptidyl-peptidase 9), or DP9, is a member of the peptidase S9B family of proteins that exhibit prolyl oligopeptidase activity. DPRP2 localizes to the cytoplasm and is ubiquitously expressed with predominant expression in heart, muscle and liver. DPRP2 may play an important role in the regulation of signaling by peptide hormones.

Function:
Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm (By similarity).

Subcellular Location:
Cytoplasm, cytosol.

Tissue Specificity:
Ubiquitously expressed, with highest levels in liver, heart and muscle, and lowest levels in brain.

Similarity:
Belongs to the peptidase S9B family. DPPIV subfamily.

SWISS:
Q86TI2

Gene ID:
91039

Database links:

Entrez Gene: 91039 Human

Entrez Gene: 224897 Mouse

Entrez Gene: 301130 Rat

Omim: 608258 Human

SwissProt: Q86TI2 Human

SwissProt: Q8BVG4 Mouse

Unigene: 515081 Human

Unigene: 205535 Mouse

Unigene: 41201 Rat



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