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Pancreatic hormone Rabbit pAb (bs-8543R)  
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50ul/1180.00元
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產品編號 bs-8543R
英文名稱 Pancreatic hormone Rabbit pAb
中文名稱 胰腺激素抗體
別    名 Pancreatic hormone precursor; Pancreatic polypeptide Y; Pancreatic prohormone; Pancreatic prohormone precursor; PNP; PP; PPY; Pancreatic prohormone; Pancreatic polypeptide; PP; INN=Obinepitide; Pancreatic hormone; PH; Pancreatic icosapeptide; PI; PAHO_HUMAN.  
Specific References  (1)     |     bs-8543R has been referenced in 1 publications.
[IF=2.694] Kate L. Lee. et al. Vesiculin derived from IGF-II drives increased islet cell mass in a mouse model of pre-diabetes. 2021 Oct 09  IHC ;  Mouse.  
研究領域 神經生物學  信號轉導  生長因子和激素  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 4 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Pancreatic hormone: 30-65/95 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma levels of this hormone have been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.

Function:
Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.
The physiological role for the icosapeptide has not yet been elucidated.

Subunit:
Belongs to the NPY family.

Subcellular Location:
Secreted.

Similarity:
Belongs to the NPY family.

SWISS:
P01298

Gene ID:
5539

Database links:
Entrez Gene: 5539 Human

Omim: 167780 Human

SwissProt: P01298 Human

Unigene: 558368 Human



產品圖片
Paraformaldehyde-fixed, paraffin embedded (Human pancreatic cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Pancreatic hormone) Polyclonal Antibody, Unconjugated (bs-8543R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.
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