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NAP1L2 Rabbit pAb (bs-11172R)  
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產品編號 bs-11172R
英文名稱 NAP1L2 Rabbit pAb
中文名稱 腦特異性蛋白BPX抗體
別    名 Brain specific gene BPX; BPX; Brain specific protein, X linked; MGC26243; Nucleosome assembly protein 1 like 2; NP1L2_HUMAN.  
研究領域 染色質和核信號  神經生物學  細胞粘附分子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAP1L2: 201-300/460 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Proper nucleosome assembly is critical for compacting DNA into chromatin. In human and mouse there are 5 protein-coding genes which comprise the nucleosome assembly protein (NAP) family. NAP1L1 (NAP1) and NAP1L4 (NAP2) are ubiquitously expressed family members which have been the most extensively studied. The remaining three family members, NAP1L2, NAP1L3 and NAP1L5 are neuron-specific nucleosome assembly proteins translated from intronless genes which are monoallelically expressed. NAP1L2 (nucleosome assembly protein 1-like 2), also known as BPX (brain specific protein, X-linked), is a 460 amino acid protein containing acidic domains which are thought to mediate histone interactions. NAP1L2 binds to chromatin and interacts with Histones H3 and H4. The function of NAP1L2 is not clearly defined although evidence suggests that NAP1L2 influences histone acetylation and therefore may play a significant role in regulating transcription in developing neurons.

Function:
NAP1L2 is a member of the nucleosome assembly protein (NAP) family.

Subcellular Location:
Nuclear

Similarity:
Belongs to the nucleosome assembly protein (NAP) family.

SWISS:
Q9ULW6

Gene ID:
4674

Database links:

Entrez Gene: 4674 Human

Entrez Gene: 17954 Mouse

Entrez Gene: 317247 Rat

Omim: 300026 Human

SwissProt: Q9ULW6 Human

SwissProt: P51860 Mouse

Unigene: 66180 Human

Unigene: 740565 Human

Unigene: 388694 Mouse

Unigene: 43670 Rat



產品圖片
25 ug total protein per lane of various lysates (see on figure) probed with NAP1L2 polyclonal antibody, unconjugated (bs-11172R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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