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CELSR3 Rabbit pAb (bs-11460R)  
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產(chǎn)品編號 bs-11460R
英文名稱 CELSR3 Rabbit pAb
中文名稱 表皮生長因子樣蛋白1/Flamingo homolog 1抗體
別    名 Cadherin EGF LAG seven-pass G-type receptor 3; Cadherin family member 11; CDHF11; CELR3_HUMAN; CELSR3; EGF-like protein 1; EGFL1; Epidermal growth factor-like protein 1; Flamingo; Flamingo homolog 1; FMI1; HFMI1; MEGF2; Multiple EGF-like domains protein 2; Multiple epidermal growth factor-like domains protein 2.  
Specific References  (1)     |     bs-11460R has been referenced in 1 publications.
[IF=2.64] Su, Lin, et al. "Deregulation of the planar cell polarity genes CELSR3 and FZD3 in Hirschsprung disease." Experimental and Molecular Pathology(2016).  IHC-P ;  Human.  
研究領域 細胞生物  神經(jīng)生物學  信號轉導  細胞粘附分子  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 354 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Flamingo homolog 1: 1601-1700/3312 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013]

Function:
Receptor that may have an important role in cell/cell signaling during nervous system formation.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 9 cadherin domains.
Contains 8 EGF-like domains.
Contains 1 GPS domain.
Contains 1 laminin EGF-like domain.
Contains 2 laminin G-like domains.

SWISS:
Q9NYQ7

Gene ID:
1951

Database links:

Entrez Gene: 1951 Human

Omim: 604264 Human

SwissProt: Q9NYQ7 Human

Unigene: 55173 Human

Unigene: 631926 Human



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