| 產品編號 | bs-11462R |
| 英文名稱 | BCAS1 Rabbit pAb |
| 中文名稱 | 乳腺癌相關蛋白1抗體 |
| 別 名 | NABC1; AIBC 1; AIBC1; Amplified and overexpressed in breast cancer; BCAS 1; BCAS1; BCAS1_HUMAN; Breast carcinoma amplified sequence 1; Breast carcinoma-amplified sequence 1; Novel amplified in breast cancer 1. |
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Specific References (2) | bs-11462R has been referenced in 2 publications.
[IF=17.694] Zhao, Ying. et al. Vascular endothelium deploys caveolin-1 to regulate oligodendrogenesis after chronic cerebral ischemia in mice. NAT COMMUN. 2022 Nov;13(1):1-20 IF ; Mouse.
[IF=6.27] Seiji Kajiet al. BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy. Acta Neuropathol Commun
. 2020 Jul 29;8(1):120. IF, WB ; rat, Human.
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| 研究領域 | 腫瘤 細胞生物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Human,Mouse,Rat) |
| 產品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 62 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BCAS1: 542-584/584 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Jul 2008] Function: Expressed in brain and prostate, and at lower levels in testis, intestine and colon. Overexpressed in most breast cancer cell lines and down-regulated in some colorectal tumors. Subunit: Homodimer. May interact with DYNLL1 and DYNLL2 Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in brain and prostate, and at lowerlevels in testis, intestine and colon. Overexpressed in most breastcancer cell lines and down-regulated in some colorectal tumors. SWISS: O75363 Gene ID: 8537 Database links: Entrez Gene: 8537 Human Omim: 602968 Human SwissProt: O75363 Human Unigene: 728940 Human |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
