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RTP3 Rabbit pAb (bs-11619R)  
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產品編號 bs-11619R
英文名稱 RTP3 Rabbit pAb
中文名稱 受體轉運蛋白3抗體
別    名 LTM1; Receptor(chemosensory) transporter protein 3; Receptor transporter protein 3; Receptor-transporting protein 3; RTP3; RTP3_HUMAN; TMEM7; Transmembrane protein 7.  
研究領域 神經生物學  細胞膜受體  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse)
產品應用 Flow-Cyt=0.2ug/test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 27 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RTP3: 21-120/232 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Members of the RTP (receptor transporter proteins) family have recently been discovered to influence bitter taste receptor expression in addition to inducing the expression of mammalian odorant receptors. RTP3 is a 232 amino acid single-pass type III membrane protein belonging to the TMEM7 family. Unlike other RTP proteins, RTP3 is not expressed in olfactory neurons but is expressed predominantly in liver. RTP3 is involved in the functional expression of bitter taste receptors and suppresses cell proliferation, and is also found in human circumvallate papillae and testis (regions where bitter taste receptors are expressed). The gene encoding RTP3 maps to human chromosome 3p21.31 within C3CER1 (chromosome 3 common eliminated region 1), which is frequently eliminated in chromosomal deletions of solid tumors.

Function:
Expressed predominantly in the liver.

Subcellular Location:
Membrane; Single-pass type III membrane protein

Tissue Specificity:
Belongs to the TMEM7 family.

Similarity:
Belongs to the TMEM7 family.

Gene ID:
83597

Database links:




產品圖片
Blank control:Molt-4. Primary Antibody (green line): Rabbit Anti-RTP3 antibody (bs-11619R) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test. Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
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