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PADI2 Rabbit pAb (bs-11662R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-11662R
英文名稱 PADI2 Rabbit pAb
中文名稱 蛋白質精氨酸亞型2抗體
別    名 PADI2/PAD2; PAD 2; PAD2; PAD H19; PAD-H19; PADI 2; Padi2; PADI2 protein; PADI2_HUMAN; PDI 2; PDI2 antibody Peptidlyarginine deiminase type II; Peptidyl arginine deiminase II; Peptidyl arginine deiminase type II; Peptidylarginine deiminase II; Protein arginine deiminase; Protein arginine deiminase type 2; Protein arginine deiminase type II; Protein-arginine deiminase type II; Protein-arginine deiminase type-2; KIAA0994; OTTHUMP00000044625.  
Specific References  (1)     |     bs-11662R has been referenced in 1 publications.
[IF=6.107] Xiao-Hu Zhao. et al. Integrative analysis reveals marker genes for intestinal mucosa barrier repairing in clinical patients. ISCIENCE. 2023 May;:106831  WB ;  Human.  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  Alzheimer's  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 76 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PADI2/PAD2: 42-120/665 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]

Function:
Catalyzes the deimination of arginine residues of proteins.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the protein arginine deiminase family.

SWISS:
Q9Y2J8

Gene ID:
11240

Database links:

Entrez Gene: 11240 Human

Entrez Gene: 18600 Mouse

Entrez Gene: 29511 Rat

Omim: 607935 Human

SwissProt: Q96DA7 Human

SwissProt: Q9Y2J8 Human

SwissProt: Q08642 Mouse

SwissProt: Q75WD0 Mouse

SwissProt: P20717 Rat

Unigene: 33455 Human

Unigene: 2296 Mouse

Unigene: 469220 Mouse

Unigene: 98523 Rat



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