超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
1级黄色大片,中国黄色片在线观看,国产尤物AV尤物在线看
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
GLUR4 Rabbit pAb (bs-12009R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-12009R
英文名稱 GLUR4 Rabbit pAb
中文名稱 離子型谷氨酸受體4抗體
別    名 Ionotropic Glutamate receptor 4; AMPA 4; AMPA selective glutamate receptor 4; AMPA-selective glutamate receptor 4; AMPA4; GluA 4; GluA4; GluR 4; GluR D; GluR-4; GluR-D; GLUR4C; GLURD; Glutamate receptor 4; Glutamate receptor ionotrophic AMPA 4; Glutamate receptor ionotropic; GRIA 4; GRIA4; GRIA4_HUMAN.  
研究領域 神經(jīng)生物學  信號轉(zhuǎn)導  通道蛋白  細胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 98 kDa
檢測分子量
細胞定位 細胞膜 細胞外基質(zhì) 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GluA4/Ionotropic Glutamate receptor 4: 351-450/902 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]

Function:
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.

Subunit:
Homotetramer or heterotetramer of pore-forming glutamate receptor subunits. Tetramers may be formed by the dimerization of dimers. Interacts with EPB41L1 via its C-terminus (By similarity). Found in a complex with GRIA1, GRIA2, GRIA3, CNIH2, CNIH3, CACNG2, CACNG3, CACNG4, CACNG5, CACNG7 and CACNG8. Interacts with CACNG5 and PRKCG

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Interaction with CNIH2, CNIH3 and PRKCG promotes cell surface expression

Post-translational modifications:
Palmitoylated. Depalmitoylated upon glutamate stimulation. Cys-611 palmitoylation leads to Golgi retention and decreased cell surface expression. In contrast, Cys-837 palmitoylation does not affect cell surface expression but regulates stimulation-dependent endocytosis.

Similarity:
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA4 subfamily.

SWISS:
P48058

Gene ID:
2893

Database links:

Entrez Gene: 2893 Human

Entrez Gene: 14802 Mouse

Entrez Gene: 29629 Rat

Omim: 138246 Human

SwissProt: P48058 Human

SwissProt: Q9Z2W8 Mouse

SwissProt: P19493 Rat

Unigene: 503743 Human

Unigene: 209263 Mouse

Unigene: 10938 Rat



版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产a一区二区 | 成人午夜视频在线观看免费 | 开心色91 | 国产综合久久99久久 | 中文字国产精久久无 | 啊灬啊灬轻点第一次和外国人 | 欧美炮房 | 欧美精品一区二区蜜臀亚洲 | 在线一区不卡 | 91夜夜夜 | 精品国产网站 | 亚洲国产主播一区 | 国产精品嫩草影院ccm | 亚洲日韩精品无码av海量 | 国产在线午夜 | 猫咪在线永久网站 | 免费观看做爰视频ⅹxx午夜 | 啪啪喷水视频 | 男人av的天堂无码专区 | 综合久久狠狠色成人网 | av成人资源网 | www.av在线| 精品毛片免费看 | 丝袜老师高潮呻吟高潮 | 国产精品禁久久精品 | 免费无套内谢少妇毛片A片软 | 亚色中文成人yase999co | 99久久久99久久国产片鸭王 | 亚洲日韩精品无码av海量 | 香蕉久久夜色精品国产尤物 | 夏目友人帐第7季高清免费观看 | 国产成AV人在线观看天堂无码 | 天天摸天天操视频 | 亚洲精品视频在线播放 | 成年人网站国产 | 日韩和欧美的一区二区 | 欧美精品久久久久久久久久丰满 | 91久久精品日日躁夜夜躁欧美 | 亚洲国产成人久久一区www妖精 | mimiai最新网站入口 | 亚洲成a人片在线不卡一二三区 |