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5HT6 Receptor Rabbit pAb (bs-12058R)  
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50ul/1180.00元
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產品編號 bs-12058R
英文名稱 5HT6 Receptor Rabbit pAb
中文名稱 5-羥色胺受體6抗體
別    名 SR-6; 5 HT 6; 5 HT6; 5 hydroxytryptamine 6 receptor; 5 hydroxytryptamine receptor 6; 5-HT-6; 5-HT6; 5-hydroxytryptamine receptor 6; 5HT 6; 5HT6R_HUMAN; HTR 6; HTR6; Serotonin receptor 6.  
Specific References  (1)     |     bs-12058R has been referenced in 1 publications.
[IF=3.707] Zhang Yuxiang. et al. The 5-HT6 Receptors in the Ventrolateral Orbital Cortex Attenuate Allodynia in a Rodent Model of Neuropathic Pain. Front Neurosci-Switz. 2020 Aug;14:884  IF ;  Rat.  
研究領域 神經生物學  細胞膜受體  G蛋白偶聯受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Pig,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 47 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human 5HT6 Receptor/SR-6: 51-150/440 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013]

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in several human brain regions, most prominently in the caudate nucleus.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P50406

Gene ID:
3362

Database links:

Entrez Gene: 3362 Human

Entrez Gene: 15565 Mouse

Entrez Gene: 64354 Rat

Omim: 601109 Human

SwissProt: P50406 Human

SwissProt: Q9R1C8 Mouse

SwissProt: P31388 Rat

Unigene: 22180 Human

Unigene: 291096 Mouse

Unigene: 10552 Rat



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