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FLRT3 Rabbit pAb (bs-12363R)  
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產品編號 bs-12363R
英文名稱 FLRT3 Rabbit pAb
中文名稱 富含亮氨酸跨膜纖連蛋白3抗體
別    名 FLRT3_HUMAN; Leucine-rich repeat transmembrane protein FLRT3; KIAA1469; Fibronectin-like domain-containing leucine-rich transmembrane protein 3; UNQ856/PRO1865;  
研究領域 發育生物學  信號轉導  干細胞  細胞分化  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Rat (predicted: Human)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 70 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FLRT3 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 FLRT3 is a 649 amino acid single-pass type I membrane protein that contains one fibronectin type-III domain and ten leucine-rich repeats and belongs to the fibronectin leucine rich transmembrane protein (FLRT) family. Expressed in heart, liver, lung, kidney, pancreas, brain, placenta and skeletal muscle, FLRT3 is thought to be involved in receptor signaling events and may play a role in both cell adhesion neurite outgrowth. Defects in the gene encoding mouse FLRT3 may lead to ventral closure, headfold fusion and endoderm migration defects, suggesting that FLRT3 is important for proper cell differentiation and development. FLRT3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 20.

Function:
May have a function in cell adhesion and/or receptor signaling.

Subcellular Location:
Membrane; Single-pass type I membrane protein (Probable).

Tissue Specificity:
Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.

Similarity:
Contains 1 fibronectin type-III domain.
Contains 10 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

SWISS:
Q9NZU0

Gene ID:
23767

Database links:

Entrez Gene: 428552 Chicken

Entrez Gene: 23767 Human

Entrez Gene: 71436 Mouse

Entrez Gene: 366205 Rat

SwissProt: F1NUK7 Chicken

SwissProt: Q9NZU0 Human

SwissProt: B1H234 Rat



產品圖片
Sample: Lane 1: Rat Cerebrum tissue lysates Lane 2: Rat Lung tissue lysates Primary: Anti-FLRT3 (bs-12363R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 70 kDa Observed band size: 73 kDa
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