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Placental lactogen I+II Rabbit pAb (bs-12940R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-12940R
英文名稱 Placental lactogen I+II Rabbit pAb
中文名稱 胎盤催乳素1/2抗體
別    名 Choriomammotropin; Chorionic somatomammotropin B; Chorionic somatomammotropin hormone 2; Chorionic somatomammotropin hormone; CS 2; CS2; CSB; CSH_HUMAN; CSH1; CSH2; hCS B; HCSB; Lactogen; mPL II; mplII; Pl 2; PL; Pl2; Placental lactogen; Placental lactogen II; Prl3b1; Prolactin 3B1; prolactin family 3, subfamily b, member 1; Placental lactogen I; Placental lactogen II; rPLII.  
研究領域 細胞生物  免疫學  發育生物學  信號轉導  生長因子和激素  內分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 22 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CSH2/Placental lactogen I/II: 110-217/217 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Placental lactogens, also referred to as chorionic somatomammotropin hormones, are protein hormones. They are produced in the mammalian placenta and are similar in structure and function to growth hormones. Together, placental lactogens and growth factors play an essential role to assure successful lactation after pregnancy. Placental lactogens also modify the metabolic state of the mother during pregnancy to supply energy to the fetus. Placental lactogen I is a member of the somatotropin/prolactin family of hormones. The proteins in this family are crucial in mammalian growth control. Placental lactogen I is expressed primarily during mid-pregnancy, and it has been reported that DNA methylation regulates its tissue expression in rats. Placental lactogen II is expressed later in pregnancy and, in mice, its secretion is regulated by the inhibitory control of GH, the concentration of which increases rapidly at the beginning of the last half of pregnancy.

Function:
Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.

Subcellular Location:
Secreted.

Similarity:
Belongs to the somatotropin/prolactin family.

SWISS:
P0DML3

Gene ID:
1443

Database links:

Entrez Gene: 1442 Human

Entrez Gene: 1443 Human

Omim: 150200 Human

SwissProt: P0DML3  Human

Unigene: 654390 Human




產品圖片
Tissue/cell: mouse placenta tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Placental lactogen I+II Polyclonal Antibody, Unconjugated(bs-12940R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: mouse embryo tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Placental lactogen I+II Polyclonal Antibody, Unconjugated(bs-12940R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: human placenta tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Placental lactogen I+II Polyclonal Antibody, Unconjugated(bs-12940R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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