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G gamma7 Rabbit pAb (bs-13246R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-13246R
英文名稱 G gamma7 Rabbit pAb
中文名稱 G蛋白偶聯受體γ7抗體
別    名 FLJ00058; GBG7_HUMAN; Gng7; GNGT7; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-7 subunit; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7.  
研究領域 腫瘤  細胞生物  信號轉導  G蛋白偶聯受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Cow,Chicken)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 7 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G gamma7: 2-65/68 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum.

Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity).

Subunit:
G proteins are composed of 3 units, alpha, beta and gamma.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed in a variety of tissues. Down-regulated in pancreatic and esophageal cancer.

Similarity:
Belongs to the G protein gamma family.

SWISS:
O60262

Gene ID:
2788

Database links:

Entrez Gene: 618399 Cow

Entrez Gene: 2788 Human

Entrez Gene: 14708 Mouse

Entrez Gene: 58979 Rat

Omim: 604430 Human

SwissProt: P30671 Cow

SwissProt: O60262 Human

SwissProt: Q61016 Mouse

SwissProt: P43425 Rat



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