超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国自产拍aⅤ在线天天更新,欧美丝袜在线观看,h视频免费在线
首頁 > 產品中心 > 一抗 > 產品信息
GAS2 Rabbit pAb (bs-13289R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-13289R
英文名稱 GAS2 Rabbit pAb
中文名稱 生長休止特定蛋白2抗體
別    名 GAS 2; GAS-2; Gas2; GAS2_HUMAN; Growth arrest specific 2; Growth arrest specific protein 2; Growth arrest-specific protein 2; MGC32610.  
研究領域 細胞生物  信號轉導  細胞凋亡  生長因子和激素  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 35 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GAS2: 141-240/313 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Gas2 is a 313 amino acid protein encoded by the human gene GAS2. Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases. Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis. The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells. Gas2 is believed to also be involved in the membrane ruffling process. During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues. Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Gas2 is mainly membrane-associated but when hyperphosphorylated it will accumulate at membrane ruffles. Gas2 is specifically expressed at growth arrest and is ubiquitously expressed with highest levels found in liver, lung and kidney. There is no evidence, however, of Gas2 expression in spleen.

Function:
May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process.

Subcellular Location:
Cytoplasm > cytoskeleton. Membrane. Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles.

Tissue Specificity:
Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen.

Post-translational modifications:
Cleaved, during apoptosis, on a specific aspartic residue by caspases.
Phosphorylated on serine residues during the G0-G1 transition phase.

Similarity:
Belongs to the GAS2 family.
Contains 1 CH (calponin-homology) domain.
Contains 1 GAR domain.

SWISS:
O43903

Gene ID:
2620

Database links:

Entrez Gene: 2620 Human

Entrez Gene: 14453 Mouse

Omim: 602835 Human

SwissProt: O43903 Human

SwissProt: P11862 Mouse

Unigene: 632151 Human

Unigene: 207360 Mouse

Unigene: 386823 Mouse

Unigene: 471773 Mouse



版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 四虎国产在线观看 | 亚洲综合免费视频 | 国产伦精品一区二区三区综合网 | 日本人在线看片免费观看 | 欧美天堂在线视频 | 久久久精品99久久精品36亚 | 天天爽夜夜爽夜夜爽视频 | 成人性生交大片免费看视 | 大又大粗又爽又黄少妇毛片免费 | 精品女同一区二区三区免费播放 | 亚洲地区天堂网 | 第一福利所导航 | 亚洲色无码中文字幕在线 | 亚洲AV色福利天堂 | 亚洲毛片在线看 | 中文字幕av伊人av无码av | www.youjizz国产| 少妇精品久久久一区二区三区 | 精品人妻无码一区二区三区手机板 | 成人午夜av国产传媒 | 精品人妻无码一区二区三区换脸 | 红杏成人免费视频观看 | 久草999 | 亚洲色欲久久久综合网 | 亚洲∧V久久久无码精品 | av无码理论片在线观看免费网站 | 精品一区二区三卡四卡网站 | 日本不卡免费一区 | 国产高清视频免费观看 | 国产精品久久777777毛茸茸 | 蜜桃无码AV一区二区 | 精品国产一区二区三区香蕉事 | 热99re久久国免费超精品首页 | 国产久操视频 | 海角国精产品一区一区三区糖心 | 亚洲午夜久久久影院 | 99热1 | 波多野结衣在线观看一区二区 | 91精品国产91久久久久久黑人 | 欧美一区二区播放 | 国产丰满老熟女一区二区三区 |