超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
一区二区三区四区影院,黄色片久久久,欧美精品一区二区三区一线天视频
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
GPCR G2A Rabbit pAb (bs-13508R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-13508R
英文名稱 GPCR G2A Rabbit pAb
中文名稱 G蛋白偶聯(lián)受體G2A抗體
別    名 G Protein Coupled Receptor G2A; G Protein Coupled Receptor G2A; G2 accumulation protein; G2A; GP132_HUMAN; GPR132; Probable G-protein coupled receptor 132.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  干細(xì)胞  細(xì)胞周期蛋白  G蛋白偶聯(lián)受體  t-淋巴細(xì)胞  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G Protein Coupled Receptor G2A: 141-240/380 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1). G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, and it is more highly detected in pro-B cells, while lower expression is observed in immature B cells and pre-B cells (1,2). G2A is expressed throughout T cell maturation, and it is further increased in response to T-cell activation (3). Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1,4). G2A is also able to attenuate the proliferative effects of Bcr-Abl, a chimeric tyrosine kinase oncogene, suggesting that G2A possesses anti-oncogenic properties (5). The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, where it is required for ubiquitination and proteolytic degradation (6).

Function:
Receptor for an unknown ligand. Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May serve as a mechanism for T- and B-cells, and other cell types, to slow their proliferation and repair damaged DNA to ensure proper replication.

Subcellular Location:
Cell membrane. Internalized and accumulated in endosomal compartments. LPC triggers the relocalization from the endosomal compartment to the cell surface.

Tissue Specificity:
Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q9UNW8

Gene ID:
29933

Database links:

Entrez Gene: 101130222 Gorilla

Entrez Gene: 29933 Human

Omim: 606167 Human

SwissProt: Q9UNW8 Human

Unigene: 532504 Human



版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 美女视频黄a视频全免费网站一区 | 国产精品一区二区三区四 | 91成品人网页进入入口 | 国产精品免费播放 | 69久久久久 | 国产免费又硬又黄又爽的视频喷水 | 国产爆乳尤妮丝无码视频在线 | 他掀开裙子舌头伸进去在线观看 | 色爱区区域综合网 | 78影视传媒有限公司 | 精品综合久久久久 | 夜色资源站www国产在线观看 | 美国人成人在线视频 | 韩国三级中文字幕HD久久精品 | 性欧美8处一14处破 欧美三级不卡在线播放 | 中文字幕在线免费97 | 国产第五页 | 少妇毛片久久久久久久久 | 日本高清视频xxxxx | 日本高清www色视频 91在线免费公开视频 | 精品国产无套在线观看 | 国产人人爱 | 欧美一级淫片a免费播放口 日韩免费一级 | 欧美a在线 | 越做高潮越喷奶水视频 | 久久久久久久久女人体 | 99精品无人区乱码1区2区3区 | x8x8女性性爽爽在线观看 | 天天爽夜夜爽夜夜爽精品视频 | 欧美视频在线观看免费 | 老师好湿好紧我要进去了在线观看 | 欧美精品一二三 | FREE性XXXX中国大陆 | 边做边爱边吃奶的视频 | 国产高清精品一区二区三区 | 夜夜爽影院 | 91视频导航 | 情侣黄网站大全免费看 | 扒开老师大腿猛进AAA片 | 久久99婷婷国产精品免费 | 国产精品久久久久久久白皙女 |