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ARPC1B Rabbit pAb (bs-10563R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-10563R
英文名稱 ARPC1B Rabbit pAb
中文名稱 肌動蛋白相關蛋白2/3復合亞單位B1抗體
別    名 ARC1B_HUMAN; Actin-related protein 2/3 complex subunit 1B; ARC41; Arp2/3 complex 41 kDa subunit; p41-ARC; actin related protein 2/3 complex subunit 1B; IMD71; PLTEID; p40-ARC;  
Specific References  (1)     |     bs-10563R has been referenced in 1 publications.
[IF=3.698] Weimin Ni. et al. Actin Related Protein 2/3 Complex Subunit 1 up-regulation in the hypothalamus prevents high-fat diet induced obesity. EUR J NEUROSCI. 2022 Nov;:  IF ;  Mouse.  
研究領域 信號轉導  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 41 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARPC1B: 101-200/372 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011]

Function:
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

Subunit:
Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.

Subcellular Location:
Cytoplasm, cytoskeleton.

Similarity:
Belongs to the WD repeat ARPC1 family.
Contains 6 WD repeats.

SWISS:
O15143

Gene ID:
10095

Database links:

Entrez Gene: 10095 Human

Entrez Gene: 11867 Mouse

Omim: 604223 Human

SwissProt: O15143 Human

SwissProt: Q9WV32 Mouse

Unigene: 489284 Human

Unigene: 30010 Mouse



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