超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日本五码在线,亚洲av永久无码精品网站在线观看,国产精品99久久久久久夜夜嗨
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
SIGIRR Rabbit pAb (bs-7361R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7361R
英文名稱 SIGIRR Rabbit pAb
中文名稱 IL-1相關(guān)Ig受體抗體
別    名 Ig IL1 related receptor; MGC110992; SIGIR_HUMAN; SIGIRR; Single Ig IL 1 related receptor; Single Ig IL-1-related receptor; Single Ig IL-1R-related molecule; Single Ig IL1R Related Molecule; Single immunoglobulin and toll interleukin 1 receptor(TIR) domain; Single immunoglobulin and toll interleukin 1 receptor domain; Single immunoglobulin domain containing IL1R related protein; Single immunoglobulin domain IL1R1 related; Single immunoglobulin domain-containing IL1R-related protein; TIR 8; TIR8; Toll/interleukin 1 receptor 8; Toll/interleukin-1 receptor 8.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 46 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIGIRR: 121-220/410 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Single Ig IL-1-related receptor SIGIRR, also designated single immunoglobulin domain-containing IL-1R-related protein or Toll/interleukin-1 receptor 8 (TIR8), is a member of the interleukin-1 receptor family. SIGIRR acts as a negative regulator of the IL-1R and Toll-like receptor signaling pathways and reduces the recruitment of certain components to the TLR4 receptor. Subsequently, SIGIRR confers resistance to P. aeruginosa corneal infection. SIGIRR can form complexes with IL-1R1, MYD-88, IRAK-1 and TRAF-6 upon IL-1 stimulation and TLR4 after LPS stimulation. It is a single-pass type III membrane protein that is mainly expressed in kidney, lung and gut.

Function:
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

Subcellular Location:
Membrane.

Tissue Specificity:
Mainly expressed in epithelial tissues such as kidney, lung and gut.

Similarity:
Belongs to the interleukin-1 receptor family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 TIR domain.

SWISS:
Q6IA17

Gene ID:
59307

Database links:

Entrez Gene: 59307 Human

Entrez Gene: 24058 Mouse

Entrez Gene: 309106 Rat

Omim: 605478 Human

SwissProt: Q6IA17 Human

SwissProt: Q9JLZ8 Mouse

SwissProt: Q4V892 Rat

Unigene: 501624 Human

Unigene: 38017 Mouse

Unigene: 16525 Rat



版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 国产伦精品一区二区三区视频金莲 | 中文在线好最新版在线 | 艳妇乳肉豪妇荡乳XXX | 亚洲人成一区 | 久久嫩草精品久久久久 | 毛片毛片毛片毛片毛片 | 不卡一区二区在线 | 开妇小嫩苞调教HHH嗯啊MTV | 99免费高清视频 | 免费av中文字幕 | 天天插狠狠干 | 中文无码一区二区不卡AV | 18禁超污无遮挡无码免费动态图 | 婷婷夜夜躁天天躁人人躁 | 久久久久国色av免费看图片 | 欧美一级特黄aaaaaa在线看片 | 亚洲高清资源在线观看 | 成人444kkkk在线观看 | 4444亚洲人成无码网在线观看 | 亚洲av中文无码乱人伦在线播放 | 欧美精品久久久久久久监狱 | 中文字幕在线观看视频免费 | a级毛片黄免费a级毛片 | 婷婷五月天.com | 日韩精品久久久免费观看四虎 | 黑人强伦姧人妻久久 | 91精品国产高清久久久久久 | 国产自在自线午夜精品 | 亚洲人成网站在线播放942 | 色综合视频一区二区三区高清 | 国产肥熟在线高清观看 | 国产美女精品AⅤ在线播放 日本三区三区三区二区二区二区高清在线 | 久草热在线 | 中文字幕在线观看精品视频 | 亚洲一区二区三区在线网站 | 狠狠爱无码一区二区三区 | 99热这里精品 | 欧洲亚洲国产一区二区 | 在线看播放免费网站 | 中文字幕最新 | 天天摸天天透天天添 |