超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
99久久久久国产精品,另类自拍偷拍,99视频在线免费看
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Diphtheria toxin fragment A Rabbit pAb (bs-10667R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-10667R
英文名稱 Diphtheria toxin fragment A Rabbit pAb
中文名稱 白喉毒素A抗體
別    名 DTX_CORBE; diphtheria toxin; NAD(+)--diphthamide ADP-ribosyltransferase(EC:2.4.2.36); EC:2.4.2.36; Diphtheria toxin fragment B; diphtheria toxin A; DTA; diphtheria toxin B; DTB;  
研究領(lǐng)域 細菌及病毒  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Corynephage beta)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 21/62 kDa
檢測分子量
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Diphtheria toxin fragment A: 21-120/567 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Diphtheria toxin is a 58 kDa protein secreted by lysogenic strains of Corynebacterium diphtheriae. The toxin causes the disease diphtheria in humans by gaining entry into the cell cytoplasm and inhibiting protein synthesis. The mechanism of inhibition involves transfer of the ADP-ribose group of NAD to elongation factor-2 (EF-2), rendering EF-2 inactive. The catalysed reaction is as follows: NAD + + peptide diphthamide = nicotinamide + peptide N-(ADP-D-ribosyl)diphthamide The crystal structure of the diphtheria toxin homodimer has been determined to 2.5A resolution. The structure reveals a Y-shaped molecule of 3 domains, a catalytic domain (fragment A), whose fold is of the alpha + beta type; a transmembrane (TM) domain, which consists of 9 alpha-helices, 2 pairs of which may participate in pH-triggered membrane insertion and translocation; and a receptor-binding domain, which forms a flattened beta-barrel with a jelly-roll-like topology. The TM- and receptor binding-domains together constitute fragment B.

Function:
Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to eukaryotic elongation factor 2 (eEF-2). Fragment A is the catalytic portion responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A.

Subcellular Location:
Homodimer.

Database links:

Entrez Gene: 2650491 CORBE

Swiss Prot: P00588 CORBE



版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产av亚洲精品久久久久 | 黑人巨大两根一起挤进a片视频 | av大全免费 | 久久久久美女 | 国产美女视频免费观看网址 | 国久久久久 | 少妇午夜三级伦理影院播放器 | 精品国产网站 | 欧美精品久久久久久久监狱 | 一区二区三区无码视频免费福利 | 日韩乱码人妻无码系列中文字幕 | 国产精品呻吟声 | 91中文字幕永久在线 | 91夜夜夜| 97国产精华最好的产品亚洲 | 97人妻免费碰视频碰免 | 国产国产成年年人免费看片 | 国产一级片免费视频 | 精品久久久久久久久久软件 | 免费看91视频| 久久r精品国产99久久6不卡 | 麻豆欧美| 国产爆乳尤妮丝无码视频在线 | 国产巨作麻豆欧美亚洲综合久久 | 成人免费ssss片 | 国产美女视频免费观看网址 | 一个人免费观看的WWW视频 | 延禧攻略在线看 | 男人女人午夜视频免费 | 美日欧激情AV大片免费观看 | 国产无吗一区二区三区在线欢 | 黄色片哪里可以看 | 国产乱人伦偷精品视频免 | 91资源免费视频 | 国产一区二区网站 | 日本免费无遮挡吸乳视频网站 | 欧美不卡在线视频 | 日本高清免费一本视频100禁 | 网站啪啪| 永久av在线 | 成年人在线免费看 |