超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
99久久久久国产精品,另类自拍偷拍,99视频在线免费看
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Diphtheria toxin fragment A Rabbit pAb (bs-10667R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-10667R
英文名稱 Diphtheria toxin fragment A Rabbit pAb
中文名稱 白喉毒素A抗體
別    名 DTX_CORBE; diphtheria toxin; NAD(+)--diphthamide ADP-ribosyltransferase(EC:2.4.2.36); EC:2.4.2.36; Diphtheria toxin fragment B; diphtheria toxin A; DTA; diphtheria toxin B; DTB;  
研究領(lǐng)域 細菌及病毒  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Corynephage beta)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 21/62 kDa
檢測分子量
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Diphtheria toxin fragment A: 21-120/567 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Diphtheria toxin is a 58 kDa protein secreted by lysogenic strains of Corynebacterium diphtheriae. The toxin causes the disease diphtheria in humans by gaining entry into the cell cytoplasm and inhibiting protein synthesis. The mechanism of inhibition involves transfer of the ADP-ribose group of NAD to elongation factor-2 (EF-2), rendering EF-2 inactive. The catalysed reaction is as follows: NAD + + peptide diphthamide = nicotinamide + peptide N-(ADP-D-ribosyl)diphthamide The crystal structure of the diphtheria toxin homodimer has been determined to 2.5A resolution. The structure reveals a Y-shaped molecule of 3 domains, a catalytic domain (fragment A), whose fold is of the alpha + beta type; a transmembrane (TM) domain, which consists of 9 alpha-helices, 2 pairs of which may participate in pH-triggered membrane insertion and translocation; and a receptor-binding domain, which forms a flattened beta-barrel with a jelly-roll-like topology. The TM- and receptor binding-domains together constitute fragment B.

Function:
Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to eukaryotic elongation factor 2 (eEF-2). Fragment A is the catalytic portion responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A.

Subcellular Location:
Homodimer.

Database links:

Entrez Gene: 2650491 CORBE

Swiss Prot: P00588 CORBE



版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: av日韩国产| 久久嫩草精品久久久精品才艺表演 | 无码毛片视频一区二区三区 | 精品国产3级a | 色网站在线观看 | 久久久精品理论A级A片 | 天堂在线国产 | 亚洲精品久久久蜜夜影视 | 婷婷久久丁香 | 国产乱对白刺激视频户外 | 久草在线免费福利资源 | 韩国av永久免费 | 正在播放白领少妇第一次 | 久久综合给合久久狠狠狠97色 | 色综合激情无码中文字幕 | 在线观看中文无码最新视频 | 久久www免费人成看片爱潮 | xxxx天堂网上xxxx| 久久嫩草 | xxxx中国一级片 | 日韩一区二区不卡 | 国产一区二区三区四区三区四 | 久久国产乱子精品免费女 | 黄色免费网站在线观看 | 97视频免费在线观看 | 99精品不卡 | 好硬啊进得太深了A片无码公司 | 国产色综合一区二区三区 | 噜噜色噜噜 | 久久99精品久久久久久久青青日本 | 久久毛片免费观看 | 亚洲精品午夜一区人人爽 | 国产999精品久久久久久绿帽 | 精品白浆一区二区三区h | 国产男女猛烈无遮挡免费视频 | 开心五月激情中文在线 | 男人的天堂Aⅴ在线无码 | 天天操天天要 | 永夜星河短剧免费观看 | 大肉大捧一进一出好爽视色大师 | 中文一国产一无码一日韩 |