超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關于我們  聯(lián)系我們
国产日韩欧美综合在线,国产精品专区在线观看,99热免费
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
eIF4A1 Rabbit pAb (bs-14547R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-14547R
英文名稱 eIF4A1 Rabbit pAb
中文名稱 eIF4A1蛋白抗體
別    名 ATP-dependent RNA helicase eIF4A-1; DDX2; DDX2A; eIF 4A I; eIF-4A-I; EIF4A; eIF4A I; eIF4A-I; EIF4A1; Eukaryotic initiation factor 4A-I; Eukaryotic initiation factor 4AI; eukaryotic translation initiation factor 4A, isoform 1; Eukaryotic translation initiation factor 4A1; IF4A1_HUMAN.  
研究領域 細胞生物  結(jié)合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Sheep,Cow,Horse,African Green Monkey)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 46 kDa
檢測分子量
細胞定位 細胞漿 細胞外基質(zhì) 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human eIF4A1: 21-120/406 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Translation initiation in eukaryotes necessitates the assembly of an 80S ribosomal complex. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that leads to 80S ribosomal assembly and initiation of translation. Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that contains eIF4A, eIF4E and eIF4G, binds mRNA at a 5’-cap motif and recruits the 43S ribosomal preinitiation complex to the eligible transcript. Along with eIF4B, the eIF4F complex mediates the unwinding of mRNA secondary structure to facilitate ribosome association. eIF4E specifically interacts with the 5’ cap, eIF4A(I,II) are bidirectional RNA helicases, and eIF4G(I,II) are scaffolding proteins which coordinate eIF4E, eIF4A, eIF3 and the 40S ribosome. Human eIF4AI (eIF4A, DDX2A) is a 406 amino acid protein that is 92.7% homologous to mouse eIF4AI. The promoter region of human eIF4A1 contains TATA and CAAT motifs and consensus binding sites to Sp1 and AP2.

Function:
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Subunit:
eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. Interacts with PAIP1, EIF4E and UPF2. Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. May interact with NOM1. Interacts with PDCD4; this interferes with the interaction between EIF4A and EIF4G. Interacts with RBM4. Interacts with human cytomegalovirus/HHV-5 protein UL69.

Similarity:
Belongs to the DEAD box helicase family. eIF4A subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.

SWISS:
P60842

Gene ID:
1973

Database links:

Entrez Gene: 1973 Human

Entrez Gene: 504958 Cow

Entrez Gene: 13681 Mouse

Entrez Gene: 287436 Rat

Omim: 602641 Human

SwissProt: Q3SZ54 Cow

SwissProt: P60842 Human

SwissProt: P60843 Mouse

Unigene: 129673 Human

Unigene: 279821 Mouse

Unigene: 371557 Mouse

Unigene: 91523 Rat



產(chǎn)品圖片
Sample: Lane 1: Human MCF-7 cell lysates Lane 2: Human HeLa cell lysates Lane 3: Human A431 cell lysates Primary: Anti-eIF4A1 (bs-14547R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kDa Observed band size: 46 kDa
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产视频一区二区三区四区 | 少妇爽到呻吟的视频 | 中文精品一区二区三区 | 午夜视频日本 | 国产av毛片一区二区三区 | 暖暖免费高清日本社区在线观看 | 日本韩国国产 | 亚洲Av日韩Aⅴ高潮潮喷无码 | 冲田杏梨AV天堂一区二区三区 | 91在现看| 亚洲欧美视屏 | 日韩一卡2卡3卡4卡新区乱码在线观看 | 一级做a爰片性色毛片 | 怡春院免费视频 | 专干日本老妇HD | 亚洲黄色在线视频 | 免费观看一级欧美片 | 狠狠爱无码一区二区三区 | 久久久久亚洲AV成人网址 | 国产精欧美一区二区三区久久 | 在线播放网址亚洲 | 性按摩aaaaaa视频| 日韩一级片免费视频 | 黄色在线观看免费 | 欧日韩精品 | 国产精品www. | 日本xxxxxxxxx96 | 综合欧美丁香五月激情 | 第一次破處在线国语视频播放 | 五月婷婷综合国产成人一区二区三区 | 国产精品免费久久久久影院仙踪林 | 野花韩国高清免费视频6 | 在线国产视频一区 | 日韩中文字幕成人免费视频 | 一区二区小视频 | 日本黄色片一级片 | 互换后人妻的呻吟晓红 | 免费观看国产美女裸体视频 | 毛片毛片毛片毛片毛片 | 超碰aⅴ人人做人人爽 | 人摸人人人澡人人超碰 |