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GPCR150 Rabbit pAb (bs-16273R)  
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50ul/1180.00元
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產品編號 bs-16273R
英文名稱 GPCR150 Rabbit pAb
中文名稱 G蛋白偶聯受體150抗體
別    名 G protein coupled receptor 150; G protein coupled receptor 160; G-protein coupled receptor GPCR1; GCPR 160; GCPR160; GP160_HUMAN; GPCR 1; GPCR 150; GPCR1; GPCR150; GPR 150; GPR 160; GPR150; Gpr160; hGPCR1; Probable G-protein coupled receptor 160; Putative G protein coupled receptor.  
研究領域 信號轉導  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 40 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPCR150: 101-200/338 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. The gene encoding GPR160 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. GPR160 expression has been shown to be up-regulated in prostate cancer.

Function:
Orphan receptor.

Subcellular Location:
Cell membrane.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q9UJ42

Gene ID:
26996

Database links:

Entrez Gene: 26996 Human

Entrez Gene: 784906 Cow

Entrez Gene: 100685878 Dog

SwissProt: Q9UJ42 Human

Unigene: 231320 Human



產品圖片
Paraformaldehyde-fixed, paraffin embedded (human cervical cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37∑C for 30min; Antibody incubation with (GPR150) Polyclonal Antibody, Unconjugated (bs-16273R) at 1:500 overnight at 4∑C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (human lung cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37℃ for 30min; Antibody incubation with (GPR150) Polyclonal Antibody, Unconjugated (bs-16273R) at 1:500 overnight at 4℃, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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