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MON2 Rabbit pAb (bs-17713R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-17713R
英文名稱 MON2 Rabbit pAb
中文名稱 MON2蛋白抗體
別    名 mon2; MON2_HUMAN; Protein MON2 homolog; Protein SF21; SF21.  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 190 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MON2: 1601-1700/1717 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 MON2 is a 1,718 amino acid protein that exists as multiple alternatively spliced isoforms and plays an important role in membrane trafficking. Related to the guanine nucleotide exchange factors (GEFs), MON2 shares significant homology with BIG as well as the GBF (Golgi brefeldin A resistance factor) subfamilies of proteins. MON2 acts as a scaffold protein when associated with Dopey-1, a large cytoplasmic protein involved in trafficking between the late golgi and early endosomes. MON2 is homologous to the yeast protein and is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Function:
May be required for traffic between late Golgi and early endosomes.

Similarity:
Belongs to the MON2 family.

SWISS:
Q7Z3U7

Gene ID:
23041

Database links:

Entrez Gene: 23041 Human

Entrez Gene: 314894 Rat

SwissProt: Q7Z3U7 Human

Unigene: 389378 Human

Unigene: 154642 Rat



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