超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
七七婷婷婷婷精品国产,国内精品视频在线播放,色五月第一门户
首頁 > 產品中心 > 一抗 > 產品信息
MUC12 Rabbit pAb (bs-17903R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-17903R
英文名稱 MUC12 Rabbit pAb
中文名稱 粘蛋白12抗體
別    名 MUC11; MUC12; Mucin 12; Mucin-12; MUC12_HUMAN.  
Specific References  (1)     |     bs-17903R has been referenced in 1 publications.
[IF=12.658] Mao, Weipu. et al. Transfection with Plasmid-Encoding lncRNA-SLERCC nanoparticle-mediated delivery suppressed tumor progression in renal cell carcinoma. J EXP CLIN CANC RES. 2022 Dec;41(1):1-19  Other ;  Other.  
研究領域 腫瘤  細胞生物  信號轉導  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 556 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MUC12: 17-200/5478 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. The mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. A family of four related Mucin genes (MUC2, MUC5AC, MUC5B and MUC6) encode the major secreted mucins. Mucin 12 contains a predicted transmembrane domain; two extracellular cysteine-rich EGF-like domains; a coiled-coil region; and a domain consisting of serine-, threonine-, and proline-rich degenerate tandem repeats of 28 amino acids, a structural feature typical of mucins. Mucin 12 transcript (>12 kb) is present in colon, pancreas, prostate and uterus. Colorectal tumors can have low Mucin 12 transcript levels in comparison to normal colon tissues.

Function:
Human MUC12 (Mucin 12) is a novel mucin of epithelial mucins, which are large, secreted or cell surface glycoproteins involved in epithelial cell protection, adhesion modulation, and signaling. Using differential display on RNA from paired normal colonic mucosa and primary colorectal tumor, MUC12 is identified as one of the 2 partial cDNAs representing novel mucin genes as well as MUC11. They are downregulated in colorectal tumors.The deduced MUC12 protein contains a predicted transmembrane domain, 2 extracellular cysteine-rich EGF-like domains, a coiled-coil region, and a domain consisting of serine-, threonine-, and proline-rich degenerate tandem repeats of 28 amino acids, a structural feature typical of mucins. Human MUC12 shares high sequence homology with MUC3 and MUC4 . Northern blot analysis of 50 different normal tissues detected MUC12 expression in colon, pancreas, prostate, and uterus, with highest expression in colon. The MUC12 transcript is large, estimated to be longer than 12 kb. Expression of MUC12 was downregulated or absent in 6 of 15 (40%) colorectal tumors, as compared with matched normal colonic tissues. MUC12 expression was not detected in any of 6 colorectal cancer cell lines examined.

Subcellular Location:
Cell Membrane

Tissue Specificity:
Ubiquitous, with higher expression in colon. Down-regulated in colorectal cancer as well as in the colon of patients with ulcerative colitis (UC) and Crohn's disease (CD).

Similarity:
Contains 1 EGF-like domain.
Contains 1 SEA domain.

SWISS:
Q9UKN1

Gene ID:
10071

Database links:

Entrez Gene: 10071 Human

Omim: 604609 Human

SwissProt: Q9UKN1 Human

Unigene: 489355 Human



版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 欧美一级特黄特色大片免费 | 三级黄色性生活视频 | 韩国久久久久久级做爰片 | 高清日韩a级毛片精品 | 久久AV高潮AV无码AV喷吹 | 天天操操夜夜操 | 毛片在线免费观看视频 | 亚洲国产精彩视频 | www.日日干| 亚洲免费观看网站 | 正在播放白领少妇第一次 | 女人一级毛片 | 少妇搡BBBB搡BBB搡野外 | 成人精品三级 | 91影院 | 后入白嫩网红内射99XYZ | 久久精品视频18 | 日韩在线视频免费看 | 欧美精品一区二区蜜臀亚洲 | 狼亚洲AV无码专区在线播放中文 | 91精品亚洲影视在线观看 | 一区二区三区中文字幕在线 | 色爱区区域综合网 | 久久青视频 | www.成人免费 | 日本免费一二三区中文 | www.youjizz.com最新 | 一区二区三区观看 | 欧美激情一区二区三区四区 | 中文日韩欧美 | 精品欧美一区二区在线观看欧美熟 | 国产一起色一起爱 | 夜夜草天天草 | 亚洲国产精品无码专区在线观看 | 亚洲aⅴ一区二区三区 | 我的性奴的肉玩具1一17心奴 | 色综合久久久久久久久五月 | 亚洲无码精品在线观看影院 | 亚洲精品久久久久一区二区三区 | 人妻少妇被粗大爽.9797pw | 91色国产|