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Orexin Receptor 1 Rabbit pAb (bs-18029R)  
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產(chǎn)品編號 bs-18029R
英文名稱 Orexin Receptor 1 Rabbit pAb
中文名稱 丘腦分泌素受體1抗體
別    名 HCRTR 1; HCRTR1; Hypocretin receptor type 1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1r; OX1R_HUMAN.  
Specific References  (3)     |     bs-18029R has been referenced in 3 publications.
[IF=5.81] Shengyan Xi. et al. The Ciji-Hua’ai-Baosheng II Formula Attenuates Chemotherapy-Induced Anorexia in Mice With H22 Hepatocellular Carcinoma. Front Pharmacol. 2021; 12: 715824  IHC ;  Mouse.  
[IF=3.333] Hye Ji J. Kim. et al. Dual Cannabinoid and Orexin Regulation of Anhedonic Behaviour Caused by Prolonged Restraint Stress. BRAIN SCI. 2023 Feb;13(2):314  IHC ;  Mouse.  
[IF=2.751] De-Qi Yan. et al. Establishment of a chronic insomnia rat model of sleep fragmentation using unstable platforms surrounded by water. EXP THER MED. 2023 May;25(5):1-12  IF ;  Rat.  
研究領(lǐng)域 腫瘤  細胞生物  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Pig,Sheep,Cow,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 48 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Orexin Receptor 1: 101-200/425 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009]

Function:
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.

Subcellular Location:
Cell membrane.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
O43614

Gene ID:
3062

Database links:

Entrez Gene: 3061 Human

Entrez Gene: 230777 Mouse

Entrez Gene: 25593 Rat

Omim: 602392 Human

SwissProt: O43613 Human

SwissProt: P58307 Mouse

SwissProt: P56718 Rat

Unigene: 388226 Human

Unigene: 246595 Mouse

Unigene: 88262 Rat



產(chǎn)品圖片
Sample: A549 Cell (Human) Lysate at 30 ug Primary: Anti-Orexin Receptor 1 (bs-18029R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48kD Observed band size: 48kD
Sample: Lane 1: Mouse Cerebellum tissue lysates Lane 2: Mouse Pancreas tissue lysates Lane 3: Rat Cerebellum tissue lysates Lane 4: Rat Pancreas tissue lysates Primary: Anti-Orexin Receptor 1 (bs-18029R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kD Observed band size: 48 kD
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