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ARFGAP2 Rabbit pAb (bs-18504R)  
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產品編號 bs-18504R
英文名稱 ARFGAP2 Rabbit pAb
中文名稱 鋅指蛋白289抗體
別    名 ADP-ribosylation factor GTPase-activating protein 2; ARF GAP 2; ARFG2_HUMAN; FLJ14576; FLJ26000; GTPase activating protein ZNF289; GTPase-activating protein ZNF289; IRZ; Nbla10535; Zfp289; Zinc finger protein 289; Zinc finger protein 289 ID1 regulated; ZNF 289.  
研究領域 轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 57 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF289/ARFGAP2: 401-500/521 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 ZNF289 functions as a GTPase-activating protein (GAP) for ARF family proteins. Localizing to the cytoplasmic side of the Golgi apparatus, ZNF289 contains one ARF-GAP domain and is found associated with COP-I-coated vesicles.

Function:
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.

Subunit:
Interacts with the coatomer complex. Interacts with the C-terminal appendage domain of COPG1.

Subcellular Location:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note: Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.

Similarity:
Contains 1 Arf-GAP domain.

SWISS:
Q8N6H7

Gene ID:
84364

Database links:

Entrez Gene: 84364 Human

Entrez Gene: 505438 Cow

Entrez Gene: 77038 Mouse

Entrez Gene: 362162 Rat

Omim: 606908 Human

SwissProt: A1L520 Cow

SwissProt: Q8N6H7 Human

SwissProt: Q99K28 Mouse

SwissProt: Q3MID3 Rat

Unigene: 436204 Human

Unigene: 43636 Mouse

Unigene: 3707 Rat



產品圖片
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-ZNF289 (bs-18504R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kD Observed band size: 57 kD
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