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ZNF622 Rabbit pAb (bs-18514R)  
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產品編號 bs-18514R
英文名稱 ZNF622 Rabbit pAb
中文名稱 鋅指蛋白622抗體
別    名 MGC108936; Zfp622; Zinc finger protein 622; Zinc finger-like protein 9; ZN622_HUMAN; ZNF622; ZPR9.  
研究領域 轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse,Rat (predicted: Human,Rabbit,Sheep,Cow,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 54 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF622: 1-100/477 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 ZNF622 (Zinc Finger Protein 622) is a Protein Coding gene. Diseases associated with ZNF622 include Autosomal Dominant Non-Syndromic Intellectual Disability 44 and Autoinflammation, Panniculitis, And Dermatosis Syndrome. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.

Function:
May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Expressed in lung, kidney, spleen, liver and brain with lowest expression in kidney.

Post-translational modifications:
Phosphorylated by MELK. The phosphorylation may redirect the protein to the nucleus.

Similarity:
Contains 2 U1-type zinc fingers.

SWISS:
Q969S3

Gene ID:
90441

Database links:

Entrez Gene: 90441 Human

Omim: 608694 Human

SwissProt: Q969S3 Human

Unigene: 60300 Human



產品圖片
25 ug total protein per lane of various lysates (see on figure) probed with ZNF622 polyclonal antibody, unconjugated (bs-18514R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZNF622) Polyclonal Antibody, Unconjugated (bs-18514R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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