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PROP1 Rabbit pAb (bs-19183R)  
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50ul/1180.00元
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產品編號 bs-19183R
英文名稱 PROP1 Rabbit pAb
中文名稱 垂體特異性同源因子抗體
別    名 CPHD2; Homeobox protein prophet of Pit 1; OTTHUMP00000161487; paired-like homeodomain transcription factor; Pituitary specific homeodomain factor; PROP 1; PROP paired like homeobox 1; prophet of Pit1.  
研究領域 細胞生物  發育生物學  神經生物學  轉錄調節因子  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 25 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PROP1: 101-180/226 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone. [provided by RefSeq, Sep 2011]

Function:
Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.

Subcellular Location:
Nucleus

DISEASE:
Combined pituitary hormone deficiency is defined as the impaired production of growth hormone and one or more of the other five anterior pituitary hormones. CPHD2 is characterized by pleiotropic deficiencies of growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone, prolactin and adrenocorticotropic hormone.

Similarity:
Belongs to the paired homeobox family.
Contains 1 homeobox DNA-binding domain.

SWISS:
O75360

Gene ID:
5626

Database links:

Entrez Gene: 5626 Human

Entrez Gene: 266738 Rat

Omim: 601538 Human

SwissProt: O75360 Human

Unigene: 158301 Human

Unigene: 86655 Rat



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