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SEC61A Rabbit pAb (bs-19618R)  
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產品編號 bs-19618R
英文名稱 SEC61A Rabbit pAb
中文名稱 轉運蛋白SEC61A抗體
別    名 chunp6898; fb62c11; HSEC61; protein transport protein SEC61 alpha subunit; protein transport protein Sec61 subunit alpha; Protein transport protein Sec61 subunit alpha isoform 1; S61A1_HUMAN; SEC 61; SEC 61A; Sec61 alpha 1; Sec61 alpha 1 subunit; Sec61 alpha 1 subunit(S. cerevisiae); Sec61 alpha-1; SEC61; Sec61 homolog; SEC61A1; sec61aa.  
研究領域 細胞生物  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse (predicted: Rat,Cow,Dog)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 52 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEC61A: 181-280/476 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]

Function:
Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins.

Subunit:
Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.

Subcellular Location:
Endoplasmic reticulum membrane.

Similarity:
Belongs to the secY/SEC61-alpha family.

SWISS:
P61619

Gene ID:
29927

Database links:

Entrez Gene: 29927 Human

Entrez Gene: 505064 Cow

Entrez Gene: 404006 Dog

Entrez Gene: 53421 Mouse

Entrez Gene: 80843 Rat

Entrez Gene: 192298 Zebrafish

Omim: 609213 Human

SwissProt: Q5EA68 Cow

SwissProt: P38377 Dog

SwissProt: P61619 Human

SwissProt: P61620 Mouse

SwissProt: P61621 Rat

SwissProt: Q90ZM2 Zebrafish

Unigene: 518236 Human

Unigene: 28375 Mouse

Unigene: 485032 Mouse

Unigene: 47029 Rat

Unigene: 51503 Zebrafish



產品圖片
Sample: A431(Human) Cell Lysate at 30 ug Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-SEC61A (bs-19618R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD
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