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SLC22A7 Rabbit pAb (bs-19808R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-19808R
英文名稱 SLC22A7 Rabbit pAb
中文名稱 溶質載體家族蛋白22成員A7抗體
別    名 hOAT2; liver specific transporter; NLT; Novel liver transporter; OAT2; Organic anion transporter 2; Organic anion transporter member 7; Organic anion transporter member 7 Fragment; S22A7_HUMAN; SLC22A7; solute carrier family 22(organic anion transporter) member 7; Solute carrier family 22; Solute carrier family 22 member 7.  
研究領域 細胞生物  免疫學  信號轉導  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 60 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC22A7: 461-548/548 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate.

Subcellular Location:
Basolateral cell membrane. Apical side of the renal tubule.

Tissue Specificity:
Expressed in liver and kidney.

Similarity:
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

SWISS:
Q9Y694

Gene ID:
10864

Database links:

Entrez Gene: 10864 Human

Entrez Gene: 108114 Mouse

Entrez Gene: 733693 Pig

Entrez Gene: 89776 Rat

Omim: 604995 Human

SwissProt: Q9Y694 Human

SwissProt: Q91WU2 Mouse

SwissProt: Q1RPP5 Pig

SwissProt: Q5RLM2 Rat

SwissProt: Q63314 Rat

Unigene: 485438 Human

Unigene: 387538 Mouse

Unigene: 10009 Rat



產品圖片
Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti- SLC22A7 (bs-19808R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 64 kD
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