超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
黑人狂虐中国人妻陈艳,日韩一二区,男人插女人免费视频
首頁 > 產品中心 > 一抗 > 產品信息
Angiotensinogen Rabbit pAb (bs-20778R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產品編號 bs-20778R
英文名稱 Angiotensinogen Rabbit pAb
中文名稱 血管緊張素原抗體
別    名 Angiotenogen; Angiotensinogen; AT; ANGT_MOUSE; Serpin A8.  
研究領域 心血管  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 49 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Angiotensinogen: 101-200/477 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Angiotensinogen protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.

Function:
Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. In response to lowered blood pressure, the enzyme renin cleaves angiotensinogen to produce angiotensin-1 (angiotensin 1-10). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2 (angiotensin 1-8). Angiotensin-1 and angiotensin-2 can be further processed to generate angiotensin-3 (angiotensin 2-8), angiotensin-4 (angiotensin 3-8). Angiotensin 1-7 is cleaved from angiotensin-2 by ACE2 or from angiotensin-1 by MME (neprilysin). Angiotensin 1-9 is cleaved from angiotensin-1 by ACE2.
Angiotensin-2 acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone.
Angiotensin-3 stimulates aldosterone release.

Subunit:
During pregnancy, exists as a disulfide-linked 2:2 heterotetramer with the proform of PRG2 and as a complex (probably a 2:2:2 heterohexamer) with pro-PRG2 and C3dg.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by the liver and secreted in plasma.

DISEASE:
Genetic variations in AGT are a cause of susceptibility to essential hypertension (EHT) [MIM:145500]. Essential hypertension is a condition in which blood pressure is consistently higher than normal with no identifiable cause.
Defects in AGT are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).

Similarity:
Belongs to the serpin family.

Database links:

Entrez Gene: 183 Human

Entrez Gene: 11606 Mouse

Entrez Gene: 24179 Rat

Omim: 106150 Human

SwissProt: P01019 Human

SwissProt: P11859 Mouse

SwissProt: P01015 Rat

Unigene: 19383 Human

Unigene: 301626 Mouse

Unigene: 6319 Rat



血管緊張素原(Angiotenogen, AT)是一種大分子糖蛋白和α2球蛋白廣泛分布于血液循環、淋巴、腦、腎臟等組織。
產品圖片
Sample: Lane 1: Plasma (Mouse) at 20 ug Lane 2: Kidney (Mouse) Lysate at 40 ug Lane 3: Adrenal gland (Mouse) Lysate at 40 ug Lane 4: Spleen (Rat) Lysate at 40 ug Lane 5: Plasma (Rat) at 20 ug Primary: Anti-Angiotensinogen (bs-20778R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50-70 kD Observed band size: 60 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Angiotensinogen) Polyclonal Antibody, Unconjugated (bs-20778R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 91色国产 | 亚洲人成网线在线播放VA蜜芽 | 亚洲精品国产精品国产 | 色青青草原桃花久久综合 | 在线视频91 | 亚洲高清国产拍精品动图 | a级欧美视频 | 美国一级在线观看 | 黄一级毛片 | 欧美性色黄大片 | 久久久久美女 | 美女视频免费是黄的网站高清 | 偷窥目拍性综合图区 | 日韩视频网站在线观看 | 久草亚洲天堂 | 偷拍自拍视频在线观看 | 蜜臀亚洲AV无码之国产精品 | 日韩欧美国产综合 | 美丽的姑娘免费播放影视大全 | 日日摸夜夜爽人人添av | 大地资源中文在线观看官网在线 | 女人体(1963) | 一区在线影院 | 亚洲三级av在线 | 蜜桃精品成人影片 | 538国产精品一区二区免费视频 | 好好的日在线视频观看 | av无码一区二区三 | 亚洲xxxxx | 日本三级吃奶头添泬播放 | 久草av一区 | 美女黄的视频全免费 | 日本黄色片在线 | 免费国产凹凸在线视频 | 欧美日韩免费在线观看 | 浓精喷进老师黑色丝袜 | 国产原创大胆私拍视频 | 超碰97人人做人人爱少妇 | 看曰本女人大战黑人视频 | 精品亚洲aⅴ一区二区三区 深夜激情视频 | 在线看黄免费 |