超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲AV无码一区二区三区在线 ,亚洲中文字幕无线无码毛片,337p欧美顶级日本大片
首頁 > 產品中心 > 一抗 > 產品信息
ITGB2 Mouse mAb (bsm-51539M)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
大包裝/詢價

產品編號 bsm-51539M
英文名稱 ITGB2 Mouse mAb
中文名稱 整合素β2/ITGB2單克隆抗體
別    名 Integrin beta 2; 95 subunit beta; CD 18; Cell surface adhesion glycoprotein LFA 1/CR3/P150, 959 beta subunit precursor); Cell surface adhesion glycoproteins LFA 1/CR3/p150, 95 subunit beta; Cell surface adhesion glycoproteins LFA-1/CR3/p150; Complement receptor C3 beta subunit; Complement receptor C3 subunit beta; Integrin beta chain beta 2; Integrin beta-2; Integrin, beta 2(complement component 3 receptor 3 and 4 subunit); ITB2_HUMAN; ITGB2; LAD; LCAMB; Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C; Leukocyte cell adhesion molecule CD18; LFA 1; LFA1; Lymphocyte function associated antigen 1; MAC 1; MAC1; MF17; MFI7; OTTHUMP00000115278; OTTHUMP00000115279; OTTHUMP00000115280; OTTHUMP00000115281; OTTHUMP00000115282.  
研究領域 腫瘤  細胞生物  細胞粘附分子  細胞表面分子  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 N17F2
交叉反應 Human
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 82 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human ITGB2 (Fragment) (His-tagged).  
亞    型 IgG1
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

Function:
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.

Subunit:
Heterodimer of an alpha and a beta subunit. Beta-2 associates with either alpha-L, alpha-M, alpha-X or alpha-D. Interacts with FGR. Interacts with COPS5 and RANBP9.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Post-translational modifications:
Both Ser-745 and Ser-756 become phosphorylated when T-cells are exposed to phorbol esters. Phosphorylation on Thr-758 (but not on Ser-756) allows interaction with 14-3-3 proteins.

DISEASE:
Leukocyte adhesion deficiency 1 (LAD1) [MIM:116920]: LAD1 patients have recurrent bacterial infections and their leukocytes are deficient in a wide range of adhesion-dependent functions. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the integrin beta chain family.
Contains 1 VWFA domain.

SWISS:
P05107

Gene ID:
3689

Database links:

Entrez Gene: 3689 Human

SwissProt: P05107 Human



產品圖片
Sample: Lane 1: K562 cell lysates Primary: Anti-ITGB2 (bsm-51538M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 82 kD Observed band size: 100 kD
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲av无码一区二区大桥未久 | 精品黑人一区二区三区久久 | 青青草成人免费 | 国产不卡一区二区在线观看 | 成成年人黄色视频网站 | 成人毛片100免费观看 | baoyu116.永久免费视频 | 国内偷拍久久 | 9区中文字幕在线 | 久章草影院 | 亚洲一区区 | 91wwwcom在线观看 | 欧美成人一区二区三区 | 日韩www在线 | 欧美在线三级 | 九色91视频 | 欧洲a老妇女黄大片 | av琪琪色 | 城中村勾搭老熟女啪啪 | 日韩一区二区免费在线观看 | 99久久综合国产精品二区 | www.日日干 | 久久久成 | 午夜性福利| 中文字幕在线视频免费视频 | 国产91网站在线观看 | 欧美大片18禁AAA免费视频 | 欧美精品久久一区二区 | 亚洲成a人片在线不卡一二三区 | 偷玩朋友的醉酒人妻中文字幕 | 中文在线播放 | 男生戳美女两腿中间那个视频 | 色偷偷成人网免费视频男人的天堂 | 中文字幕永久视频在线看 | 后入内射欧美99二区视频 | 国产在线看 | 久久精品爱爱视频 | 91麻豆精品国产91久久久点播时间 | 中国久久 | 久久福利网站 | 粉色视频在线免费观看 |