超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
黄色污在线,91看片免费版,欧美精品一区二区不卡
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
CD20 Rabbit pAb (bs-25072R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)

產(chǎn)品編號 bs-25072R
英文名稱 CD20 Rabbit pAb
中文名稱 CD20抗體
別    名 CD20_HUMAN; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; MS4A1; MS4A2; B1; CVID5; LEU-16; S7.  
研究領(lǐng)域 腫瘤  免疫學(xué)  干細(xì)胞  細(xì)胞表面分子  細(xì)胞類型標(biāo)志物  淋巴細(xì)胞  b-淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD20: 121-220/297 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit.

Function:
This protein may be involved in the regulation of B-cell activation and proliferation

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed on B-cells.

Post-translational modifications:
Phosphorylated. Might be functionally regulated by protein kinase(s).

DISEASE:
Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low.

Similarity:
Belongs to the MS4A family.

SWISS:
P11836

Gene ID:
931

Database links:

Entrez Gene: 931 Human

Omim: 112210 Human

SwissProt: P11836 Human

Unigene: 712553 Human



[PHARMACEUTICAL] Monoclonal antibodies (mAb) against CD20 are used to treat B-cell non-Hodgkin lymphoma (NHL). These antibodies include Rituximab (Mabthera), Britumomab (Zevalin) and Tositumomab (Bexxar). CD20 engaged by mAb can generate transmembrane signals capable of directly controlling cell growth and triggering cell death in certain tumors. Alternatively, mAb can mediate complement-dependent cytotoxicity. B淋巴細(xì)胞標(biāo)志物 CD20是B細(xì)胞特異性抗原,其表達(dá)呈細(xì)胞類型一種質(zhì)膜蛋白質(zhì),參與信號傳導(dǎo)作用,此抗體識別大多數(shù)B細(xì)胞上的一種抗原。多用于標(biāo)記B淋巴細(xì)胞及B細(xì)胞淋巴瘤。 CD20一般不與T細(xì)胞交叉反應(yīng),對B細(xì)胞淋巴瘤和急慢性淋巴細(xì)胞白血病等有較好的細(xì)胞特異性,因此在惡性淋巴瘤,尤其是T或B細(xì)胞淋巴瘤的分類上,CD20是最常用的B細(xì)胞標(biāo)志。
產(chǎn)品圖片
Sample: Lane 1: Human Raji cell lysates Lane 2: Human Ramos cell lysates Primary: Anti-CD20 (bs-25072R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 33 kDa Observed band size: 45 kDa
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 97超碰精品成人国产 | 天堂网WWW在线资源中文 | 男女午夜猛烈啪啦啦视频 | 欧美精品理论片大全 | 国产一级片免费视频 | 四虎成人精品国产永久免费 | 99热这里只有精品免费播放 | 人成久久| 无码人妻丰满熟妇区免费 | 亚洲色无码中文字幕在线 | 国产美女视频免费观看网址 | 欧美精品久久一区二区 | 大地资源网中文第五页 | 国产日产欧洲无码视频无遮挡 | 国产丰满老熟女一区二区三区 | 免费看av在线网站网址 | 农村少妇好紧水多视频 | 911精品影院在线观看 | 中文字幕av三区 | 给我看高清的视频在线观看片 | 国产精品久久免费视频 | 93久久精品日日躁夜夜躁欧美 | 久久免费公开视频 | 国产精品一区二区视频 | 天堂va蜜桃 | 另类视频一区二区三区 | 殴美性猛交 | 中国精品偷拍区偷拍无码 | 亚洲1级片 | 熟妇人妻无码中文字幕老熟妇 | 国产精品俺来也在线观看 | 日本不卡影院 | 成年无码av动漫网站天堂网 | 日韩一区二区免费在线观看 | 国精无码欧精品亚洲一区 | 国产精品中文 | 国产亚洲欧美另类在线第1页 | 91传媒麻豆激情在线观看 | 久久无码高潮喷水免费看 | 亚洲综合欧美动漫丝袜图 | 男人j捅女人p |