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phospho-BHMT1(Thr45) Rabbit pAb (bs-39011R)  
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產(chǎn)品編號(hào) bs-39011R
英文名稱 phospho-BHMT1(Thr45) Rabbit pAb
中文名稱 磷酸化BHMT抗體
別    名 BHMT1(phospho T45); BHMT1(phospho-Thr45); p-BHMT1(Thr45); betaine homocysteine methyltransferase; betaine homocysteine S methyltransferase 1; betaine homocysteine S methyltransferase; betaine--homocysteine S-methyltransferase 1; BHMT1; BHMT1_HUMAN; EC 2.1.1.5; Epididymis secretory sperm binding protein Li 61p; HEL S 61p.  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse,Rat
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human BHMT1 around the phosphorylation site of Thr45 : PW(p-T)PE 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq, Jul 2008]

Function:
Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Found exclusively in liver and kidney.

Similarity:
Contains 1 Hcy-binding domain.

SWISS:
Q93088

Gene ID:
635

Database links:


產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded Human Kidney Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-BHMT1(Thr45) Polyclonal Antibody, Unconjugated (bs-39011R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRPand DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-BHMT1(Thr45) Polyclonal Antibody, Unconjugated (bs-39011R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRPand DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-BHMT1(Thr45) Polyclonal Antibody, Unconjugated (bs-39011R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRPand DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Rat Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-BHMT1(Thr45) Polyclonal Antibody, Unconjugated (bs-39011R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRPand DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Mouse Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-BHMT1(Thr45) Polyclonal Antibody, Unconjugated (bs-39011R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRPand DAB (C-0010) staining.
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