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TNFRSF12A/CD266 Recombinant Rabbit mAb (bsm-52646R)  
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50ul/1400.00元
100ul/2500.00元
大包裝/詢價
產品編號 bsm-52646R
英文名稱 TNFRSF12A/CD266 Recombinant Rabbit mAb
中文名稱 腫瘤壞死因子配體超家族成員12A(CD266)重組兔單抗
別    名 CD 266; CD266; CD266 antigen; TWEAKR; FGF inducible 14; FGF-inducible 14; Fibroblast growth factor inducible immediate early response protein 14; Fibroblast growth factor-inducible immediate-early response protein 14; FN 14; FN14; TNFRSF 12A; TNR12_HUMAN; Tumor necrosis factor receptor superfamily member 12A; TWEAK R; Tweak receptor; Tweak-receptor; TweakR; Type I transmembrane protein Fn 14; Type I transmembrane protein Fn14.  
研究領域 腫瘤  心血管  細胞生物  免疫學  信號轉導  生長因子和激素  細胞膜受體  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 2C14
交叉反應 Human,Mouse,Rat
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 11 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 A synthesized peptide derived from human CD266: 81-129 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 TWEAK (otherwise known as TNFRSF12A, Tumor necrosis factor receptor superfamily member 12A), is a member of the TNF family and was first described as a weak inducer of apoptosis in some cell types. It is thought to promote angiogenesis and the proliferation of endothelial cells as well as modulating cellular adhesion to matrix proteins. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library.
Function : Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.

SWISS:
Q9NP84

Gene ID:
51330

Database links:

Entrez Gene: 51330 Human

Entrez Gene: 27279 Mouse

Entrez Gene: 302965 Rat

SwissProt: Q9NP84 Human

SwissProt: Q9CR75 Mouse



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