| 產品編號 | bsm-63188R |
| 英文名稱 | phospho-Beta catenin (S33/S37) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化β連環素蛋白重組兔單抗 |
| 別 名 | CTNB1_HUMAN; Catenin beta-1; catenin beta 1; CTNNB1; Catenin beta; Beta-catenin; CTNNB; OK/SW-cl.35; PRO2286; EVR7; MRD19; NEDSDV; armadillo; βcatenin; β catenin; β-catenin; |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | 5A11 |
| 交叉反應 | Human,Rat |
| 產品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 85 kDa |
| 檢測分子量 | 92 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human beta Catenin around the phosphorylation site of S33/S37: LD-pS-GIH-pS-GA |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. SWISS: P35222 Gene ID: 1499 細胞粘附蛋白（Call Adhesion Protein） β連環素蛋白β-catenin是一種多功能的蛋白質，能鏈接E-\N-,鈣粘附分子具有參與細胞粘附和介導信號轉導的雙重功能，并與腫瘤的發生發展及浸潤密切相關。 在正常個體中，β-catenin和鈣黏蛋白形成復合體，介導同型細胞的粘附，維持細胞的穩定；同時，β-catenin作為Wnt/β-catenin信號通路的關鍵成員在介導信號轉導過程中調控細胞的增殖和凋亡。 在惡性腫瘤中，β-catenin的表達呈現明顯的異質性，促使細胞異常增殖，還可使細胞之 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
