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Rabbit Anti-Wnt8b/PE-Cy3 Conjugated antibody (bs-6245R-PE-Cy3)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6245R-PE-Cy3
英文名稱 Rabbit Anti-Wnt8b/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的WNT蛋白家族Wnt8b抗體
別    名 Protein Wnt-8b; Wingless related MMTV integration site 8b; Wingless type MMTV integration site family, member 8B; Wnt 8b; Wnt8 b; Wnt8b; WNT8B_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  神經生物學  信號轉導  干細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Wnt8b
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.

Function:
Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.

Subcellular Location:
Secreted

Tissue Specificity:
Expression is restricted to the brain, and more specifically to the forebrain.

Similarity:
Belongs to the Wnt family.

Database links:

Entrez Gene: 7479 Human

Entrez Gene: 538720 Cow

Entrez Gene: 486841 Dog

Entrez Gene: 100070360 Horse

Omim: 601396 Human

SwissProt: Q93098 Human

Unigene: 421281 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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