超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
在线观看一区二区三区视频,99视频精品免视看,伊人色综合久久天天网图片
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-DOK3/AP Conjugated antibody (bs-6234R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6234R-AP
英文名稱 Rabbit Anti-DOK3/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的對接蛋白3抗體
別    名 Docking protein 3; DOK 3; DOK Like Protein; DOKL Pending; Downstream of tyrosine kinase 3; p62 DOK Like Protein; DOK3_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  信號轉導  轉錄調節因子  激酶和磷酸酶  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Cow, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DOK3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl functionDOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function. There are 4 isoforms generated by alternative splicing.

Function:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with

Subunit:
On tyrosine phosphorylation, interacts with CSK and INPP5D/SHIP1 via their SH2 domains. Both Tyr-381 and Tyr-398 are required for interaction with INPP5D. Only Tyr-381 is required for interaction with CSK. Binds ABL1 through the PTB domain and in a kinase-dependent manner. Does not interact with RasGAP (By similarity).

Subcellular Location:
Cytoplasm (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity).

Tissue Specificity:
Expressed in spleen.

Post-translational modifications:
Constitutively tyrosine-phosphorylated (By similarity).
On IL2 stimulation, phosphorylated on C-terminal tyrosine residues possibly by Src kinases. Can also be phosphorylated by ABL1 kinase (By similarity).

Similarity:
Belongs to the DOK family. Type A subfamily.
Contains 1 IRS-type PTB domain.
Contains 1 PH domain.

Database links:

Entrez Gene: 79930 Human

Entrez Gene: 27261 Mouse

Entrez Gene: 306760 Rat

Omim: 611435 Human

SwissProt: Q7L591 Human

SwissProt: Q9QZK7 Mouse

SwissProt: B2RYG7 Rat

Unigene: 720849 Human

Unigene: 33910 Mouse

Unigene: 19911 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产在线不卡2005 | 欧美xxxx三人交性视频 | 大量情侣在线偷拍小视频 | 久久久久久综合网天天 | 一区二区三区欧洲 | 韩国久久久久久级做爰片 | 国产91影院 | 久久99精品国产麻豆婷婷洗澡 | 18禁无码无遮挡在线播放 | 日韩欧美高清DVD碟片 | 成人黄色免费大片 | 久久久久女人 | 91嫩操| 久久久久女| 91精品国产爱久久丝袜脚 | 国产最新一区 | 久久国产中文娱乐网 | 91福利精品第一导航禁漫天堂 | 久久久一牛精品99久久精品66 | 97人妻免费碰视频碰免 | 国产中文三级全黄 | www.aa456.com亚洲 天天综合入口 | 日韩国产精品无码一区二区三区 | 久久精品99国产 | 中国按摩xxxx做受a | 久久精品国产68国产精品亚洲 | 国产丝袜无码免费视频 | 国产精品三区www17con | 93人妻人人揉人人澡人人 | 久无码久无码AV无码 | 手机看片日本 | 国产精品久久久麻豆 | 成人影院在线免费观看 | 精品产国自在拍 | 亚洲成a人在线观看 | 国产成人女人在线观看 | 日韩欧美五区 | 精品人妻系列无码天堂 | 国产亚洲精品久久久久久郑州 | 亚洲成a人片在线不卡一二三区 | 曰韩无码二三区中文字幕 |