| 產品編號 | bs-1436R-Gold |
| 英文名稱 | Rabbit Anti-PBP/Gold Conjugated antibody |
| 中文名稱 | 膠體金標記的磷脂酰乙醇胺結合蛋白1抗體 |
| 別 名 | phosphatidylethanolamine-binding protein; PEBP; PEBP 1; PBP; RKIP; Phosphatidylethanolamine-binding protein 1; PEBP-1; PEBP1; Prostatic-binding protein; Prostatic binding protein; Neuropolypeptide h3; HCNPpp; Raf kinase inhibitor protein; Hippocampal cholinergic neurostimulating peptide; HCNP. |
| 規格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領域 | 腫瘤 細胞生物 神經生物學 信號轉導 細胞周期蛋白 轉錄調節因子 激酶和磷酸酶 表觀遺傳學 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 產品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 21kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RKIP |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產品介紹 |
background: Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor. [SUBCELLULAR LOCATION] Cytoplasm. Belongs to the phosphatidylethanolamine-binding protein family. Function: Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor. Subcellular Location: Cytoplasm. Similarity: Belongs to the phosphatidylethanolamine-binding protein family. Database links: Entrez Gene: 5037 Human Entrez Gene: 23980 Mouse Omim: 604591 Human SwissProt: P30086 Human SwissProt: P70296 Mouse Unigene: 433863 Human Unigene: 195898 Mouse Unigene: 338476 Mouse Unigene: 473809 Mouse Unigene: 29745 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 信號傳導（Signaling Intermediates） Raf激酶抑制蛋白(PKIP)屬于磷脂酰乙醇胺結合蛋白 （phosphatidylethanolamine-binding protein, PEBP）家族,廣泛存在于各種不同的生物中,PKIP還參與了對NF-kB信號通路和G蛋白偶聯受體信號通路的調控,參與NF-κB信號通路的調控,參與了對細胞內多種信號轉導通路的調節作用。RKIP在膜的生物合成、精子發生、神經發育和細胞凋亡等生理過程中發揮重要作用，并參與了老年癡呆癥及糖尿病等的病理過程。有學者認為：RKIP有抑制腫瘤細胞轉移的作用。 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
