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Mouse Anti-HBeAg(2E6)/APC Conjugated antibody (bsm-2023M-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bsm-2023M-APC
英文名稱 Mouse Anti-HBeAg(2E6)/APC Conjugated antibody
中文名稱 APC標記的人乙型肝炎e抗原單克隆(檢測)抗體
別    名 Core antigen; Core protein; HBe antigen; HBeAg; HBVgp4; Pre C,C; Precore protein; Precore/core; Precore/core ORF; Precore/core protei; HBEAG_HBVD3; External core antigen; HBeAg; p25.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 免疫學  細菌及病毒  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 2E6
交叉反應
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 HBeAg full length protein
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.

Function:
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.

Subunit:
Homodimerizes.

Subcellular Location:
Secreted. Host nucleus.

Post-translational modifications:
Phosphorylated.
Cleaved by host furin.

Similarity:
Belongs to the orthohepadnavirus precore antigen family.

Database links:

Entrez Gene: 944568 Hepatitis B virus

SwissProt: Q89714 Hepatitis B virus



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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