超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
gogogo在线播放中国,精品国产资源,中文字幕无码乱码人妻系列蜜桃
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Frizzled 2/HRP Conjugated antibody (bs-6623R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6623R-HRP
英文名稱 Rabbit Anti-Frizzled 2/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標記的Wnt信號受體FZD2蛋白抗體
別    名 Frizzled homolog 2; Frizzled-2; Frizzled2; Fz 2; Fz-2; Fz2; FZD 2; FZD2; FZD2_HUMAN; FzE 2; FzE2; hFz 2; hFz2.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  干細胞  轉錄調節因子  G蛋白偶聯受體  細胞表面分子  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Rabbit, )
產品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Frizzled 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled as well as several secreted mammalian frizzled-related proteins (FRPs) have been described. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt and are generally coupled to G proteins. Expression of frizzled-2 can be observed in the fetal kidney and lung and in the adult ovary and colon. The Wnt/cGMP/Ca2+ pathway is mediated by frizzled-2 . It binds Wnt proteins and signals by activating the release of stored calcium. Expression of frizzled-2 is regulated by Angiotensin II. Activated frizzled-2 suppresses the activity of protein kinase G, and activates NFAT-dependent transcription, the phosphatidylinositol pathway and calcium sensitive enzymes.

Function:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Subcellular Location:
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely expressed. In the adult, mainly found in heart, placenta, skeletal muscle, lung, kidney, pancreas, prostate, testis, ovary and colon. In the fetus, expressed in brain, lung and kidney. Low levels in fetal liver.

Post-translational modifications:
Ubiquitinated by ZNRF3, leading to its degradation by the proteasome (By similarity).

Similarity:
Belongs to the G-protein coupled receptor Fz/Smo family.
Contains 1 FZ (frizzled) domain.

Database links:

Entrez Gene: 2535 Human

Entrez Gene: 57265 Mouse

Entrez Gene: 64512 Rat

Omim: 600667 Human

SwissProt: Q14332 Human

SwissProt: Q9JIP6 Mouse

SwissProt: Q08464 Rat

Unigene: 142912 Human

Unigene: 597264 Human

Unigene: 36416 Mouse

Unigene: 92324 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久亚洲色WWW成人图片 | 国产精品久久久aaa 欧美乱强伦XXXXX | 在线国产精品一区二区 | 99久久免费国产精品四虎 | 午夜久久久久久久久 | 久久精品国产免费看久久精品 | 麻豆精品免费在线观看 | gay男同帅哥网站在线观看 | 亚洲AV无码乱码在线观看看 | 人妻丰满熟AV无码区HD | 新超碰在线| 久久国产中文娱乐网 | 天堂网WWW在线资源最新版 | 国产精品国产三级国产aⅴ中文 | 无码国产精品一区二区VR老人 | 一级做a爰片欧美激情床 | 丝袜老师高潮呻吟高潮 | 男生戳美女两腿中间那个视频 | 久久久麻豆精品一区二区 | 国色天香综合网 | 亚洲一区二区三区写真 | 欧美精品九九99久久 | 在线观看中文字幕一区二区 | 日本iv一区二区三区 | 三上悠亚公侵犯344在线观看 | 91艹逼视频 | 91国自产精品中文字幕亚洲 | 亚洲国产国产亚洲一二三 | 嗯快点别停舒服好爽受不了了 | 少妇挑战三个黑人惨叫4p国语 | 无遮无码免费裸交视频 | 国内av在线| 99视频久久| 51社区在线成人免费视频 | 国产精品av久久久久久久久久 | 成人无码av免费网站 | 一区二区三区在线视频播放 | 综合一区在线 | 久久在现 | 九色pron| 亚洲免费高清 |