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Rabbit Anti-SDCCAG8/BF647 Conjugated antibody (bs-7011R-BF647)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7011R-BF647
英文名稱 Rabbit Anti-SDCCAG8/BF647 Conjugated antibody
中文名稱 BF647標記的結腸癌抗原8抗體
別    名 Antigen NY CO 8; CCCAP; Centrosomal colon cancer autoantigen protein; HSPC085; NPHP10 gene; NY-CO-8; Serologically defined colon cancer antigen 8; Serologically defined colon cancer antigen 8 homolog; SLSN7 gene; SDCG8_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  細胞類型標志物  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 83 kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SDCCAG8
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The exact function of SDCCAG8 remains unknown. It is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.

Function:
Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis.

Subunit:
Homodimer (By similarity). Interacts with OFD1; the interaction is direct. Interacts with FAM161A.

Subcellular Location:
Isoform 2: Cytoplasm.

Tissue Specificity:
Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.

DISEASE:
Defects in SDCCAG8 are the cause of Senior-Loken syndrome type 7 (SLSN7) [MIM:613615]. SLSN7 is a renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life.

Database links:
UniProtKB/Swiss-Prot: Q86SQ7.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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