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Rabbit Anti-THRSP/BF488 Conjugated antibody (bs-6738R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6738R-BF488
英文名稱 Rabbit Anti-THRSP/BF488 Conjugated antibody
中文名稱 BF488標記的甲狀腺激素反應蛋白抗體
別    名 Lpgp; LPGP1; S14; S14 protein; SPOT 14; Spot 14 protein; SPOT14; SPOT14 homolog; Thrsp; THRSP_HUMAN; Thyroid hormone inducible hepatic protein; Thyroid hormone responsive (SPOT14 homolog rat); Thyroid hormone responsive; Thyroid hormone responsive protein; Thyroid hormone responsive SPOT14; Thyroid hormone-inducible hepatic protein.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human THRSP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.Mainly expressed in tissues that synthesize triglycerides.

Function:
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.

Subunit:
Homodimer. Heterodimer with MID1IP1. Interacts with THRB and PLAGL1.

Subcellular Location:
Cytoplasm.Nucleus.

Tissue Specificity:
Mainly expressed in tissues that synthesize triglycerides.

Similarity:
Mainly expressed in tissues that synthesize triglycerides.
Belongs to the SPOT14 family.

Database links:

Entrez Gene: 7069 Human

Entrez Gene: 21835 Mouse

Entrez Gene: 25357 Rat

Omim: 601926 Human

SwissProt: Q92748 Human

SwissProt: Q62264 Mouse

SwissProt: P04143 Rat

Unigene: 591969 Human

Unigene: 28585 Mouse

Unigene: 81140 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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