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Rabbit Anti-HFH4/BF488 Conjugated antibody (bs-1775R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1775R-BF488
英文名稱 Rabbit Anti-HFH4/BF488 Conjugated antibody
中文名稱 BF488標記的叉頭蛋白J1抗體
別    名 Forkhead box protein J1; FOXJ-1; winged helix; FOXJ1; FKHL13; HFH-4; HFH4; MGC35202; forkhead box J1; Forkhead Homologue 4; Forkhead related protein FKHL13; Fox J1; Hepatocyte nuclear factor 3 forkhead homolog 4; HNF-3/forkhead homolog 4; FOXJ1_HUMAN.   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  轉錄調節因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat,  (predicted: Dog, Cow, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FOXJ1 C-terminus
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[provided by RefSeq, Sep 2009]

Function:
May play an important role in cell fate determination during lung development and in spermatogenesis.

Subcellular Location:
Nucleus.

Tissue Specificity:
Testis, oviduct, lung and brain cortex.

DISEASE:
Genetic variations in FOXJ1 may be associated with susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.

Similarity:
Contains 1 fork-head DNA-binding domain.

Database links:

Entrez Gene: 2302 Human

Entrez Gene: 15223 Mouse

Entrez Gene: 116557 Rat

Omim: 602291 Human

SwissProt: Q92949 Human

SwissProt: Q61660 Mouse

SwissProt: Q63247 Rat

Unigene: 651204 Human

Unigene: 378938 Mouse

Unigene: 202954 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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