超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲综合久久av一区二区三区,日韩视频网址,草免费视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-LCAT/Cy5.5 Conjugated antibody (bs-1972R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1972R-Cy5.5
英文名稱 Rabbit Anti-LCAT/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的卵磷酯膽固醇酰基轉移酶抗體
別    名 LCAT; LCAT_HUMAN; Lecithin cholesterol acyltransferase; Lecithin-cholesterol acyltransferase; Phosphatidylcholine sterol acyltransferase; Phosphatidylcholine-sterol acyltransferase; Phospholipid cholesterol acyltransferase; Phospholipid-cholesterol acyltransferase.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  心血管  免疫學  神經生物學  信號轉導  激酶和磷酸酶  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LCAT
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency. [provided by RefSeq, Jul 2008]

Function:
Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms.

Subcellular Location:
Secreted. Note=Secreted into blood plasma. Produced in astrocytes and secreted into cerebral spinal fluid (CSF).

Tissue Specificity:
Expressed mainly in brain, liver and testes. Secreted into plasma and cerebral spinal fluid. Expressed in Hep-G2 cell line.

Post-translational modifications:
O- and N-glycosylated. O-glycosylation on Thr-431 and Ser-433 consists of sialylated galactose beta 1-->3N-acetylgalactosamine structures. N-glycosylated sites contain sialylated triantennary and/or biantennary complex structures.

DISEASE:
Lecithin-cholesterol acyltransferase deficiency (LCATD) [MIM:245900]: A disorder of lipoprotein metabolism characterized by inadequate esterification of plasmatic cholesterol. Two clinical forms are recognized: complete LCAT deficiency and fish-eye disease. LCATD is generally referred to the complete form which is associated with absence of both alpha and beta LCAT activities resulting in esterification anomalies involving both HDL (alpha-LCAT activity) and LDL (beta-LCAT activity). It causes a typical triad of diffuse corneal opacities, target cell hemolytic anemia, and proteinuria with renal failure. Note=The disease is caused by mutations affecting the gene represented in this entry.
Fish-eye disease (FED) [MIM:136120]: A disorder of lipoprotein metabolism due to partial lecithin-cholesterol acyltransferase deficiency that affects only alpha-LCAT activity. FED is characterized by low plasma HDL and corneal opacities due to accumulation of cholesterol deposits in the cornea ('fish-eye'). Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the AB hydrolase superfamily. Lipase family.

Database links:

Entrez Gene: 3931 Human

Entrez Gene: 16816 Mouse

Entrez Gene: 24530 Rat

Omim: 606967 Human

SwissProt: P04180 Human

SwissProt: P16301 Mouse

SwissProt: P18424 Rat

Unigene: 387239 Human

Unigene: 1593 Mouse

Unigene: 10481 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

LCAT是參與體內脂質代謝的主要成份之一,是一種在高密度脂蛋白(HDL)代謝和動脈粥樣硬化(AS)發展中的關鍵酶。LCAT需要經載脂蛋白ApoAI、載脂蛋白D(ApoD)作為輔助因子并經ApoE活化來發揮作用。
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久激情欧美 | 精品少妇爆乳无码专区久久 | 国产精品美女www爽爽爽 | 日韩精品一区在线播放 | 男人的天堂日本 | 成年女美黄网站大全免费播放 | 您好星期六2024最新免费观看 | 丝袜国偷自产中文字幕亚洲第一页 | 欧美人与拘一级a毛片 | 天天躁日日躁狠狠的躁天龙影院 | 无遮挡边摸边吃奶边做视频 | 欧美寡妇xxxx黑人猛交玩 | 女人19毛片一级毛片 | 黄色免费观看视频 | 在线综合色| 91精品婷婷国产综合久久 | 欧美成人精品二区三区99精品 | 日韩精品无码一二区A片换脸 | 在线观看黄色免费 | 91caoprom最新超碰地址 | 久久99精品久久久久久久青青日本 | 亚洲一区在线免费 | 亚洲人成网7777777国产 | 麻豆视传媒 | 亚洲AV永久无码精品表情包 | 91精品国产色综合久久 | 日韩毛片在线看 | 午夜不卡影院 | 波多野结衣中文AV无码专区 | 日韩国产精品一区二区 | 亚洲综合麻豆 | 爱色av网 | zzijzzij亚洲日本少妇熟睡 | 日本三级免费片 | 中国一级毛片免费观看 | 少妇性BBB搡BBB爽爽爽视频 | 中文字幕乱在线伦视频中文字幕乱码在线 | 成人精品av一区二区三区网站 | 97人人做人人人难人人做 | 亚洲大片精品永久免费 | 137大胆人体在线观看 |