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Rabbit Anti-ROM1/BF488 Conjugated antibody (bs-11125R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11125R-BF488
英文名稱 Rabbit Anti-ROM1/BF488 Conjugated antibody
中文名稱 BF488標記的視網(wǎng)膜感光細胞外節(jié)膜蛋白1抗體
別    名 Retinal outer segment membrane protein 1; Rod outer segment membrane protein 1; ROM; ROM1; ROM1_HUMAN; ROSP1; RP7; Tetraspanin 23; Tetraspanin-23; Tspan 23; Tspan-23; TSPAN23.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學  細胞粘附分子  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Cat, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ROM1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008].

Function:
May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.

DISEASE:
Defects in ROM1 may cause retinitis pigmentosa (RP); when associated with defects in PRPH2.

Similarity:
Belongs to the PRPH2/ROM1 family.

Database links:
UniProtKB/Swiss-Prot: Q03395.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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