超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
他掀开裙子舌头伸进去在线观看 ,国产片性视频免费播放,天天色综合色
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Cryptochrome 1/BF594 Conjugated antibody (bs-11441R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11441R-BF594
英文名稱 Rabbit Anti-Cryptochrome 1/BF594 Conjugated antibody
中文名稱 BF594標記的隱花色素蛋白1抗體
別    名 Cryptochrome I; CRY1; CRY1_HUMAN; Cryptochrome 1 (photolyase like); Cryptochrome 1; Cryptochrome-1; Cryptochrome1; PHLL1; Photolyase-like.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  轉錄調節因子  通道蛋白  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 64kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cryptochrome 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Circadian clocks are biological timepieces that regulate hormonal rhythms, sleep cycles and feeding behaviors. These rhythms are generated in the superchiasmatic nucleus (SCN), a cell-autonomous circadian oscillator located within the brain that is synchronized with the environment by light. A number of transcription factors, including Clock and BMAL1, are molecular components of the SCN that induce the expression of proteins involved in light/dark cycle entrainment, which include Per1 and Per2. Tim, for timeless, generates a negative feedback loop that regulates the activity of Clock by suppressing the expression of Clock target genes. Tim forms heterodimers with Per1 and Per2 that bind Clock and block the activation of Clock-BMAL1 dimers to repress Per gene expression. Additionally, the CRY proteins, which are cryptochrome photoreceptors for the circadian clock, function as light-independent inhibitors of the circadian clock. CRY1 and CRY2 negatively regulate SCN components by associating with the activators Clock-BMAL1, and also with the various feedback inhibitors Per1, Per2 and Tim.

Function:
Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK.

Subunit:
Component of the circadian core oscillator, which includes the CRY proteins, CLOCK or NPAS2, ARNTL or ARNTL2, CSNK1D and/or CSNK1E, TIMELESS, and the PER proteins. Interacts directly with TIMELESS and the PER proteins. Interacts directly with PER1 and PER2 C-terminal domains. Interaction with PER2 inhibits its ubiquitination and vice versa. Binds MAPK. Interacts with FBXL21 (By similarity). Interacts with FBXL3.

Subcellular Location:
Cytoplasm. Nucleus. Translocated to the nucleus through interaction with other Clock proteins such as PER2 or ARNTL.

Post-translational modifications:
Phosphorylation on Ser-247 by MAPK is important for the inhibition of CLOCK-ARNTL-mediated transcriptional activity. Phosphorylation by CSNK1E requires interaction with PER1 or PER2. Phosphorylation at Ser-71 and Ser-280 by AMPK destabilizes it.
Ubiquitinated by the SCF(FBXL3) and SCF(FBXL21) complex leading to degradation.

Similarity:
Belongs to the DNA photolyase class-1 family.
Contains 1 DNA photolyase domain.

Database links:

Entrez Gene: 1407 Human

Omim: 601933 Human

SwissProt: Q16526 Human

Unigene: 151573 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 黄色毛片av | 日本天天躁狠狠躁噜噜噜 | 色八区人妻在线视频 | 成年人网站国产 | 艳母1-6在线播放 | 日日日日日日日 | 永久免费av在线 | 成人免费视频源码网站 | 亚洲日本高清成人AⅤ片 | 亚洲成人一区在线观看 | 四虎小视频| 午夜裸体女人视频网站在线观看 | 超鹏97国语 | 精品人妻无码一区二区三区手机板 | 久久久久久久久久久久中文字幕 | 东京久久久 | 少妇精品久久久一区二区三区 | 精品美女久久久久 | 大地资源网中文第五页 | 纯欧美一级毛片免费 | 成人午夜精品久久久久久久3d | 成年人视频在线免费 | 亚洲欧美日韩精品久久亚洲区色播 | 91九色精品 | 国产精品Va免费视频 | 91天堂国产在线 | 久久影院一区二区 | 最近2018免费中文字幕4 | 性荡视频播放在线视频7777 | caoporn超碰最新公开 | 超清无码无卡中文字幕 | 日本乱子伦xxxx | 天天干天天弄 | 欧美性猛交xxxx乱大交俱乐部 | 97无码免费人妻超级碰碰碰碰 | 日本视频网站在线观看 | 国产一级义婬片AAA毛片久久 | 亚洲日本欧美天堂在线手机版 | 91播放在线| 最新在线视频 | 成人无码A片一区二区三区免费看 |